P-Values

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

At P-Values, you’ll find updates, perspective, insights and information from staff and partners working on the frontlines of research, advocacy and implementation. P-value is a statistical term for the probability that a trial result is reliable and not the outcome of chance. 

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Global Health Watch: Exec Order Changes Childhood Vaccine Recs, $2B in Faith-based Aid, NIH Restricts Policy Rx

This week, the US Administration announced $2 billion in global health funding for faith-based organizations; US Congress intensified oversight of PEPFAR and the bilateral global health agreements; the NIH moves to restrict policy-focused research; and – perhaps most alarmingly – the US President issued an executive order rewriting longstanding, evidence-based childhood vaccine recommendations.

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Global Health Watch: Fauci in Contempt + New NIAID Director, Senate Blocks OMB’s Grant Proposal, New CDC Director, AIDS 2026 Highlights

This week, the US Senate Committee on Homeland Security & Governmental Affairs voted along party lines to hold Anthony Fauci in contempt of Congress for his refusal to answer questions during last week’s hearing on the COVID-19 response testimony – while it was rumored that Steven Quay, a lab-leak proponent, is in line for Fauci’s old job. At the same time, the US Senate Appropriations Committee did step up to stop the White House OMB’s politicization of federal research grants. There’s also – finally – a new leader of the US Centers for Disease Control and Prevention (CDC). And the HIV/AIDS community is unpacking major themes emerging from the AIDS 2026 conference.

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AVAC Says Stop the Waste, Fraud and Abuse in the Persecution of Tony Fauci 

AVAC vehemently opposes the decision by the U.S. Senate Homeland Security and Governmental Affairs Committee to hold Dr. Anthony Fauci in contempt for his refusal to answer questions during last week’s hearing on the COVID-19 response. Certain members of the committee have made clear their intentions to pin the shortcomings of the U.S. response to COVID-19 on others by blaming and dragging renowned government scientists and public health practitioners such as Dr. Fauci through politicized proceedings without any evidence and using conspiratorial conjecture.

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Global Health Watch: Exec Order Changes Childhood Vaccine Recs, $2B in Faith-based Aid, NIH Restricts Policy Rx

This week, the US Administration announced $2 billion in global health funding for faith-based organizations; US Congress intensified oversight of PEPFAR and the bilateral global health agreements; the NIH moves to restrict policy-focused research; and – perhaps most alarmingly – the US President issued an executive order rewriting longstanding, evidence-based childhood vaccine recommendations.

August 2026

Global Health Watch: Fauci in Contempt + New NIAID Director, Senate Blocks OMB’s Grant Proposal, New CDC Director, AIDS 2026 Highlights

This week, the US Senate Committee on Homeland Security & Governmental Affairs voted along party lines to hold Anthony Fauci in contempt of Congress for his refusal to answer questions during last week’s hearing on the COVID-19 response testimony – while it was rumored that Steven Quay, a lab-leak proponent, is in line for Fauci’s old job. At the same time, the US Senate Appropriations Committee did step up to stop the White House OMB’s politicization of federal research grants. There’s also – finally – a new leader of the US Centers for Disease Control and Prevention (CDC). And the HIV/AIDS community is unpacking major themes emerging from the AIDS 2026 conference.

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August 2026

AVAC Says Stop the Waste, Fraud and Abuse in the Persecution of Tony Fauci 

AVAC vehemently opposes the decision by the U.S. Senate Homeland Security and Governmental Affairs Committee to hold Dr. Anthony Fauci in contempt for his refusal to answer questions during last week’s hearing on the COVID-19 response. Certain members of the committee have made clear their intentions to pin the shortcomings of the U.S. response to COVID-19 on others by blaming and dragging renowned government scientists and public health practitioners such as Dr. Fauci through politicized proceedings without any evidence and using conspiratorial conjecture.

August 2026

Beyond AIDS 2026: AVAC’s Top 10

Following the AIDS 2026 conference in Rio de Janeiro, our team compiled a list of AVAC’s top 10 takeaways. These topics sparked discussions and ideas among our team and AVAC’s larger partner network, and will carry our work well into the future.

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August 2026

AIDS 2026: Rising Above to Meet the Moment 

Following AIDS 2026 in Rio de Janeiro, AVAC’s Executive Director Mitchell Warren reflects on a week of conversations, sessions, and new data. As he puts it, Rio was a reminder that science has never been stronger, communities have never been more ready, and the need has never been more urgent. Ending HIV is no longer limited by what we know, it is limited only by the courage to act.

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August 2026

Global Health Watch: Fauci Testifies as AIDS 2026 Wraps Up, Gavi Receives its Funding & New Policy Restricts Gain-of-Function Research

Scientists and advocates gathered in Rio for the 26th International AIDS Conference (AIDS 2026) this week to discuss the future of the HIV response, just as former NIAID Director Anthony Fauci appeared before a hostile Senate Committee on Homeland Security & Governmental Affairs, reminding us that the greatest barriers to ending HIV are increasingly political, not scientific. In addition, this week’s issue covers the US Administration’s use of vaccine funding as leverage in negotiations with Gavi and a new policy restricting gain-of-function research.

July 2026

Science, Systems, and Communities: Turning Progress into Impact

As the AIDS 2026 conference enters its second half, one message has emerged above all others: the barriers to ending HIV are no longer primarily scientific; they are political. Read on for AVAC’s highlights so far at the conference.

July 2026

Innovation Without Access is Injustice: AIDS 2026 Opens in Rio

“Innovation without access is injustice.” That message, delivered during Monday evening’s opening ceremony of the 26th International AIDS Conference (AIDS 2026) captured the defining theme emerging from the first days of the meeting. As scientific innovation accelerates with new prevention options, cure research and long-acting antiretroviral treatment advancing, advocates, researchers, health officials and donors are warning that shrinking funding, unequal access and fragile delivery systems threaten to undermine decades of progress. The message is clear: scientific innovation alone will not end the epidemic.

July 2026

Global Health Watch: First real-world PEPFAR disruption data, long-term LEN results, US foreign assistance, HIV supply chain vulnerabilities

New evidence ahead of next week’s International AIDS Conference continues to illustrate the challenges and opportunities facing the global HIV response. This week’s issue covers the first real-world evidence of PEPFAR disruptions, new data reinforcing the long-term potential of lenacapavir for HIV PrEP (LEN), the emerging US foreign assistance architecture and a timely analysis of the vulnerabilities facing HIV medicine supply chains.

July 2026

AVAC and Access Bridge Applaud Monthly PrEP Pill Access Announcement; Call for Speed, Scale and Equity in Future Monthly Oral Alimatravir Introduction

AVAC and Access Bridge applaud Merck’s announcement today that it has granted seven direct licenses to generic manufacturers to produce their investigational monthly pill for HIV prevention, known as MK-8527, or alimatravir, while Phase 3 clinical trials are still enrolling. “Today’s news reflects truly positive momentum in future access to alimatravir for PrEP, if proven safe and effective,” said Mitchell Warren, AVAC’s executive director.

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July 2026

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P-Values Blog

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

Advocates Network

AVAC’s email list for organization and individuals interested in timely updates and critical perspectives on developments in biomedical HIV prevention.

Weekly News Digest

A comprehensive round-up of HIV prevention media coverage and scientific publications.

PxPulse

Each month this podcast uses interviews, discussion and first-person reflections to explore vital topics confronting the field of HIV prevention research.

PxWire

PxWire is AVAC’s quarterly update on biomedical HIV prevention. Each issue highlights key developments, challenges and opportunities, and features a centerspread infographic that provides a visual tool for framing these issues.

Pandemic Watch

Pandemic Watch is a curated news digest on the latest pandemic prevention, preparedness, and response (PPPR) news and resources.

Press Releases

A collection of official statements from AVAC.

AVAC in the News

Media clippings featuring AVAC, its staff and close partners in the news media.