P-Values

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

At P-Values, you’ll find updates, perspective, insights and information from staff and partners working on the frontlines of research, advocacy and implementation. P-value is a statistical term for the probability that a trial result is reliable and not the outcome of chance. 

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Global Health Watch: France Cuts Global Fund, US Bilateral Health Platform, PEPFAR Timeline Uncertainty, New Lancet Africa Journal

This week, France sharply cut its contribution to the Global Fund, adding to the replenishment shortfall. Meanwhile, the US launched a new global health funding platform tied to bilateral agreements, even as delays in MoUs and shifting timelines continue uncertainty about service delivery. And the inaugural issue of The Lancet Regional Health – Africa launched to elevate African leadership in health research and policy.

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Global Health Watch: France Cuts Global Fund, US Bilateral Health Platform, PEPFAR Timeline Uncertainty, New Lancet Africa Journal

This week, France sharply cut its contribution to the Global Fund, adding to the replenishment shortfall. Meanwhile, the US launched a new global health funding platform tied to bilateral agreements, even as delays in MoUs and shifting timelines continue uncertainty about service delivery. And the inaugural issue of The Lancet Regional Health – Africa launched to elevate African leadership in health research and policy.

March 2026

AVAC Roundup

The last few weeks have been action-packed for HIV prevention (and for AVAC and partners), with unpacking data and discussions from CROI; injectable lenacapavir for PrEP (LEN) rolling out in a number of Eastern and Southern Africa countries; signings (and not) of “America First” Bilateral Health Agreements; and our latest quarterly STI and HIV updates. AVAC is tracking it all; see below for the key updates.

March 2026

My CROI 2026 Notebook: Science, Surprises, and the Big Question of Choice 

VAC Regional Program Manager for Research Engagement Grace Kumwenda shares her CROI 2026 notebook—covering the rapidly expanding menu of long-acting prevention options, innovative delivery models bringing PrEP closer to communities, and the big question running through it all: how much choice is enough, and are our systems ready to deliver it?

March 2026

CROI 2026: Hot Takes

Returning to the CROI conference after several years, AVAC Senior Program Manager Cindra Feuer gives her reflections on a field that’s leaner, fiercer, and fighting back—from promising long-acting ARV pipelines to a striking 70% HIV incidence decline in the SEARCH trial and a spirited PEP Think Tank on what comes next.

March 2026

Global Health Watch: US Appropriated Science Funds Remain Frozen, Lenacapavir Rollout Advances + South Africa Pursues Local Production

In this issue, we look at delays in the release of US science funding, despite congressional approval, and new developments from South Africa and AVAC shaping the global rollout of HIV prevention options. 

March 2026

Introducing Access Bridge, Our Partner in Product Introduction

AVAC is excited to introduce Access Bridge. Incubated over the past decade at AVAC as part of our Product Introduction and Access team, Access Bridge is an independent, Kenya-based nonprofit organization advancing timely, sustainable and equitable introduction of and access to HIV prevention, sexual reproductive health and related health products.

March 2026

Global Health Watch: Zimbabwe steps away from US health MoU, new domestic funding in SA, LEN launched in Kenya + Zim, investment case for Global Fund

This week’s issue covers Zimbabwe’s decision to halt negotiations on its Memorandum of Understanding with the US for global health funding; new domestic funding in South Africa; a new investment case for US funding for the Global Fund; the launch of LEN in Kenya and Zimbabwe; and key takeaways from CROI 2026.

February 2026

CROI 2026: Meaningful Progress, Expanding Choice

AVAC’s continued coverage of CROI summarizes key themes from the final two days of the conference, including the vital importance of choice and steps needed to make choice a reality.

February 2026

CROI 2026: Science, Solidarity and High Stakes for the HIV Response 

CROI 2026 opened with a sobering message and defiant acknowledgment. Against a backdrop of funding cuts, dismantled programs, and growing political interference, speakers on the first two days of CROI warned that interrupting support for HIV research “is not a policy choice; it threatens infrastructures that took decades to build.” 

February 2026

Global Health Watch: Leadership Changes at US Health Agencies, Global Fund Replenishment and What’s Next for Vaccine Regulation

This week, we reflect on the escalating war on science. Two recent pieces illustrate how budget decisions and policy priorities are reshaping US scientific and global health leadership and undermining the stability of programs relied on by hundreds of millions of people. We also track the consolidation of power across US health agencies, mounting uncertainty in vaccine regulation, and the Global Fund’s ongoing replenishment.

February 2026

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P-Values Blog

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

Advocates Network

AVAC’s email list for organization and individuals interested in timely updates and critical perspectives on developments in biomedical HIV prevention.

Weekly News Digest

A comprehensive round-up of HIV prevention media coverage and scientific publications.

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Press Releases

A collection of official statements from AVAC.

AVAC in the News

Media clippings featuring AVAC, its staff and close partners in the news media.