P-Values

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

At P-Values, you’ll find updates, perspective, insights and information from staff and partners working on the frontlines of research, advocacy and implementation. P-value is a statistical term for the probability that a trial result is reliable and not the outcome of chance. 

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Global Health Watch: Global Governance Shifts, ACIP Charter + Vaccine Policy, PEPFAR Transition

As many in the United States pause to commemorate Independence Day – and, hopefully, re-commit to the fundamental principles of democracy – the global health community continues to navigate the far-reaching effects of US policy decisions. Institutions are changing, governance is being redefined and the systems that have underpinned the global HIV response are being reshaped. This issue covers developments in global health governance, the continued restructuring of US vaccine policy and growing concerns that PEPFAR’s transition is outpacing the systems needed to sustain it.

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Blog Post

Protecting Science. Advancing HIV Prevention. Preparing for What's Next | New AVAC Resources

Global health is being reshaped by rapid geopolitical shifts, scientific breakthroughs and the growing role of artificial intelligence — creating both new opportunities and new challenges. Translating scientific breakthroughs into impact requires protecting research, advancing equitable access and ensuring communities are at the center. Explore AVAC’s latest resources to help navigate and shape what comes next.

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Blog Post

From Anticipation to Action: The Civil Society Advocates' Checklist for Lenacapavir for PrEP 

The most recent option in HIV prevention is injectable lenacapavir for PrEP – a six-monthly subcutaneous injection. To ensure community leadership is at the center of this rollout, the Advocates’ Checklist for Lenacapavir for PrEP Introduction helps CSOs and global health advocates pressure-test government commitments, map implementation bottlenecks and demand equitable access.

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Global Health Watch: Global Governance Shifts, ACIP Charter + Vaccine Policy, PEPFAR Transition

As many in the United States pause to commemorate Independence Day – and, hopefully, re-commit to the fundamental principles of democracy – the global health community continues to navigate the far-reaching effects of US policy decisions. Institutions are changing, governance is being redefined and the systems that have underpinned the global HIV response are being reshaped. This issue covers developments in global health governance, the continued restructuring of US vaccine policy and growing concerns that PEPFAR’s transition is outpacing the systems needed to sustain it.

July 2026

Protecting Science. Advancing HIV Prevention. Preparing for What’s Next | New AVAC Resources

Global health is being reshaped by rapid geopolitical shifts, scientific breakthroughs and the growing role of artificial intelligence — creating both new opportunities and new challenges. Translating scientific breakthroughs into impact requires protecting research, advancing equitable access and ensuring communities are at the center. Explore AVAC’s latest resources to help navigate and shape what comes next.

July 2026

From Anticipation to Action: The Civil Society Advocates’ Checklist for Lenacapavir for PrEP 

The most recent option in HIV prevention is injectable lenacapavir for PrEP – a six-monthly subcutaneous injection. To ensure community leadership is at the center of this rollout, the Advocates’ Checklist for Lenacapavir for PrEP Introduction helps CSOs and global health advocates pressure-test government commitments, map implementation bottlenecks and demand equitable access.

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June 2026

The Future Won’t Build Itself: Sustaining the Movement CASPR Started

Join AVAC and partners for a webinar on Tuesday, July 14 to hear the impact stories of ten years of the Coalition to Accelerate and Support Prevention Research (CASPR). We will share wins, discuss lessons for the field and provide perspectives on the future of HIV prevention advocacy with AVAC’s global network.

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June 2026

Global Health Watch: New Political Declaration on HIV/AIDS, End of US PEPFAR Support for South Africa + Treatment Declines

This week, UN member states adopted a new Political Declaration on HIV/AIDS reaffirming global commitments to end AIDS by 2030, but the US notably voted against it. At the same time, the US announced a phase-out of PEPFAR support for South Africa and new analyses show PEPFAR-supported HIV treatment declined in 2025, following the US Administration’s foreign aid freeze.

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June 2026

Global Health Watch: Restructuring PEPFAR, Political Control Over Science; FDA + African Medicines Agency MoU

This week, the US Administration continues to move to consolidate control over science, restructure the systems that underpin PEPFAR and global health security, and redefine US global health engagement through regulatory influence rather than long-term public health partnerships.

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June 2026

UN High-Level Meeting on HIV/AIDS

UN member states and agencies will meet June 22 and 23 for the 2026 UN High-Level Meeting on HIV/AIDS (HLM) with the goal of charting a path toward ending AIDS as a public health threat by 2030. Read on for what to watch for.

June 2026

Global Health Watch: Political Interference in Science, Bethesda Declaration 2.0, UN HLM on HIV Negotiations, ADA Mtg Controversy

From the updated Bethesda Declaration and controversy at the American Diabetes Association annual meeting, to high-stakes negotiations on the UN Political Declaration on HIV/AIDS ahead of the upcoming High-Level Meeting, the politicization of science and public health are on full display this week.

June 2026

HIV Cure Research

As scientific progress accelerates, AVAC’s cure programs are ensuring communities remain at the center of the agenda. Through initiatives like the US HIV Cure Academy, global advocacy convenings and community-led storytelling, AVAC is equipping advocates with the knowledge and networks needed to shape the future of HIV cure research and bridge the gap between complex science and the communities most impacted by HIV.

June 2026

The 2026 US HIV Cure Academy

In April 2026, AVAC, the Well Project and the Martin Delaney Collaboratories brought together skilled advocates together, along with leading researchers and cure experts, for the US HIV Cure Academy. The Academy is designed to strengthen understanding of HIV cure science and build research translation skills in support of advocacy efforts. Learn more.

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June 2026

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P-Values Blog

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

Advocates Network

AVAC’s email list for organization and individuals interested in timely updates and critical perspectives on developments in biomedical HIV prevention.

Weekly News Digest

A comprehensive round-up of HIV prevention media coverage and scientific publications.

PxPulse

Each month this podcast uses interviews, discussion and first-person reflections to explore vital topics confronting the field of HIV prevention research.

PxWire

PxWire is AVAC’s quarterly update on biomedical HIV prevention. Each issue highlights key developments, challenges and opportunities, and features a centerspread infographic that provides a visual tool for framing these issues.

Pandemic Watch

Pandemic Watch is a curated news digest on the latest pandemic prevention, preparedness, and response (PPPR) news and resources.

Press Releases

A collection of official statements from AVAC.

AVAC in the News

Media clippings featuring AVAC, its staff and close partners in the news media.