The latest edition of Protecting Global Gains profiles an effort in Benin that may stave off a feared spike in malaria due to disrupted healthcare support during COVID-19.

The recently released WHO World Malaria Report 2020 highlights what is at stake if COVID-19 derails malaria prevention and treatment efforts—models estimate malaria deaths in sub-Saharan Africa could nearly double in 2020. A Better Way to Distribute Bed Nets explores how health officials in Benin are adapting and deploying new technologies to bring mosquito-blocking bed nets exactly where they are needed, despite the pandemic. These innovations will reap public-health benefits well beyond COVID-19.

Bed nets are to malaria what masks are to COVID-19: simple tools that can be extremely effective, but only if people have access to them and use them properly—a particular challenge in the midst of pandemic restrictions. To address this, health officials with Benin’s National Malaria Control Program, in collaboration with Catholic Relief Services (CRS), are using geotagged data to deliver bed nets door-to-door. By combining digital technology with community-based health practice, the Ministry of Health has distributed more than 7 million bed nets to 3 million households—in the middle of a COVID-19 lockdown.

While this approach was adopted out of necessity, it also removes barriers for households who may not have had the ability to travel to a distribution site, and points the way to community-based delivery of a whole range of basic health services, including HIV medications and family planning supplies.

Follow the Protecting Global Gains series on social media at @hivpxresearch, @theglobalfight, @Amref_Worldwide and #ProtectingGlobalGains, and consider amplifying these stories on your own social media. Advocates can call for national and international action to reinvigorate the fight against malaria and support critical work to distribute mosquito nets. Visit www.protectingglobalgains.org to learn more about how to take action.

This December 1st is a busy one for AVAC—in addition to being World AIDS Day, it also marks our 25th anniversary advocating for the ethical development and accelerated delivery of HIV prevention options that work for the people who need them most. And this year it’s also #GivingTuesday.

It’s a time of tremendous change, challenge and possibility. AVAC and our partners have been forging a path through this shifting terrain with our eyes on a transformational and utterly achievable goal—equity-driven pandemic preparedness at the global level.

Far-sighted evidence-based, human-rights-centered advocacy has always been at the heart of AVAC’s work, since we began advocacy for the ethical development of an HIV vaccine in 1995. Check out our timeline for a snapshot of our work and milestones in the field over the past 25 years.

In AVAC’s letter marking World AIDS Day, we stake out three actions as 2021 advocacy priorities—program for choice, invest in cadres of community health workers, and pursue equitable access to essential health products and services. These priorities draw from our knowledge that progress against HIV has been remarkable and highly unequal. That important but uneven progress is now threatened by the ravages of COVID-19, which in turn stems from a world that has so far failed to invest in the systems that forestall pandemics.

At AVAC, our programs, partnerships, publications, convenings and advocacy tools are framing the issues, helping to identify opportunities to advance the work, and supporting a cadre of informed advocates to engage with global health decision-makers. Our advocacy priorities for HIV prevention demand a similar determination to apply what we’ve learned to global pandemics writ large, to protect the global gains and usher in a newly possible equitable response to pandemics.

Your contribution supports:

• Grassroots organizing by and for young women who know the options they need
• Rigorous, data-driven campaigns to shift policies and targets at country and global level
• A cadre of LGBT and key population activists committed to ensuring human rights in biomedical strategies
• Analysis, infographics and explanatory materials for today’s most complex topics from research to rollout of biomedical interventions for HIV and COVID-19

This #GivingTuesday, we hope you’ll consider supporting this work!

There are several ways to share your financial support:

• Donate via our website: Visit www.avac.org/donate.
• Amazon Smile: Shop at Amazon.com Visit smile.amazon.com and select AVAC as your charity of choice and a portion of your purchase price is donated to AVAC—at no additional cost to you!
• US Combined Federal Campaign: If you are a US government employee, support our mission through the Combined Federal Campaign, CFC #12308.

As Winnie Byanyima, Executive Director of UNAIDS, said in reference to their new report Prevailing against pandemics by putting people at the centre, “No country can defeat these pandemics on its own. A challenge of this magnitude can only be defeated by forging global solidarity, accepting a shared responsibility and mobilizing a response that leaves no one behind. We can do this by sharing the load and working together.”

Please consider supporting AVAC if you can, and we look forward to working with you going forward!

In this new edition of Protecting Global Gains, learn how an innovative approach to HIV care and treatment has helped Malawi better weather the impact of COVID-19. This latest story comes in the lead up to World AIDS Day—with this year the world commemorating the fight against one pandemic in the midst of another. World AIDS Day also provides an opportunity to reflect on work to protect hard-won gains against HIV during a global public health crisis.

In Malawi, people who have been taking HIV medication for at least six months and have a stable viral load can take home a multi-month supply of medications, which reduces the need to travel to the clinic. This kind of differentiated service delivery (DSD) has proven to be an essential lifeline during COVID-19.

DSD models for treatment and prevention—teams of community health workers, mobile clinics, support networks and supply chains—will all be as critical to the fight against COVID-19 as they are to efforts to end AIDS. These are the systems and services that people already know and trust—and must be protected, sustained, and built upon to combat COVID-19, protect global health gains, and reimagine a brighter public health future.

In the short-term, advocates can demand policies and programs that make it easier for people to access health care, testing and treatment, for HIV and for COVID-19, and ensure that vulnerable and marginalized groups are included in decision-making.

Follow us on social media at @hivpxresearch, @theglobalfight and @Amref_Worldwide and #protectglobalgains, and consider amplifying these stories on your own social media. Visit www.protectingglobalgains.org to learn how to take action and to share your stories of innovation in the time of COVID.

With the prospect of a new US Presidential administration, it’s time to identify innovations in the US and overseas that can help fight COVID and improve public health. Our latest update of Protecting Global Gains is a reminder that low-income countries have the experience, wisdom and inclination toward innovation that can save lives in wealthier nations.

In the latest edition in our series, learn how the state of Massachusetts is working with Partners in Health (PIH) to apply lessons from PIH’s epidemic responses in places like Haiti, Rwanda and Sierra Leone to offer care and support to people in quarantine.

America’s profit-driven health system has long prioritized medical and clinical services, even though community-led and -based solutions are drivers of health. With guidance from PIH, Massachusetts has invested in a corps of caregivers who follow up with individuals isolating or in quarantine after COVID-19 contact tracing. Non-medical support such as food, medicine, cleaning supplies, rental assistance and legal advice is helping people remain at home, boosting the reach and impact of contact tracing.

Katie Bollbach, director of PIH’s newly created US Public Health Accompaniment Unit, describes the effort as “an inflection point to reconsider and reimagine the health systems we need for the future.”

This is just one example of community-centered public health that is making a difference. Learn about other interventions that are succeeding in protecting public health in the midst of COVID-19 from our series, Protecting Global Gains, a initiative we are implementing in partnership with Amref Health Africa and Friends of the Global Fight Against AIDS, TB and Malaria.

Follow us on social media at @hivpxresearch, @theglobalfight and @Amref_Worldwide and #protectglobalgains, and consider amplifying these stories on your own social media. Visit www.protectingglobalgains.org to learn how to take action and to share your stories of innovation in the time of COVID.

By AVAC Executive Director Mitchell Warren and first appeared in Devex.

The news last week and again this week that at least two highly effective vaccines may be on the horizon is a welcome respite from the devastating impact of COVID-19 on global health. In under a year, SARS-CoV-2 has already caused more than 56 million infections and 1.3 million deaths.

Any true analysis of the pandemic’s toll, however, must go beyond those devastating numbers to include the impact of COVID-19 on childhood immunizations, sexual and reproductive health, noncommunicable disease programs and global efforts to reduce HIV, tuberculosis, malaria and countless other diseases. With HIV alone, COVID-19 has diminished access to critical prevention and treatment supplies such as condoms and antiretroviral drugs, shuttered clinics and reduced testing.

Now it appears that an intensive biomedical research effort is producing tools that could help to turn the COVID-19 pandemic around. This welcome and exciting news should be balanced by some important lessons from the HIV experience on the challenges of turning highly effective prevention tools into real and accessible options for people in need.

With HIV, a long-standing commitment to research that engages and respects the communities in which it is conducted has begun paying exceptional dividends in HIV prevention research, even in the midst of this new pandemic. The most recent of these is the success of long-acting cabotegravir injections in slowing HIV infections in both men and women — also big news this month.

Other recent advances include the positive European regulatory opinion on the dapivirine vaginal ring, a promising new HIV prevention option for women; the launch of the Mosaico HIV vaccine trial; and the upcoming release of data from AMP — meaning “antibody mediated prevention” — the first large-scale human study of HIV antibodies to reduce the risk of infection. On the user side, surprising increases in the uptake of PrEP, or preexposure prophylaxis, show that coronavirus-related access barriers are not enough to dampen demand for effective HIV prevention.

The decades of research and advocacy that led to these achievements in HIV provide important lessons for global responses to COVID-19 and other pandemics as well.

The first of these is that dedicated, collaborative, sustained and well-funded research can truly turn a pandemic around. Such an effort has produced treatments that allow people living with HIV to live full, healthy lives, along with a range of effective prevention strategies, including condoms, PrEP, clean needles, harm reduction and voluntary medical male circumcision.

The work to find, fund and ensure community-led delivery of these strategies has been long, challenging and resource-intensive — but it has also produced extraordinary results.

Another critical lesson: Complex health challenges defy simple, single-agent solutions. COVID-19 will not end by a vaccine alone. Instead, as with HIV, defeating this pandemic will require a harm reduction approach in which people have access to and are able to choose a combination of strategies that work for them, understanding that many tools reduce but do not necessarily eliminate risk.

Harm reduction can only work when it is supported by clear public health messages and freely available supplies — such as condoms, clean needles and PrEP for HIV, or masks, hand sanitizer and personal protective equipment for COVID-19. As both diseases show, inconsistent or politicized public health messaging, inequitable access to the options people need to protect themselves, and insufficient testing are only likely to heighten and prolong crises.

Ignoring the third lesson has prevented many countries from achieving epidemic control of HIV and threatens to do the same with COVID-19: Interventions that work beautifully in the lab or clinical trial can only have real-world impact if they respond to the needs of their intended users, are trusted by communities, and are readily available in a context free from stigma and discrimination.

The HIV experience shows that exceptional scientific progress is just one step in the complex effort to control a pandemic. Trust in biomedical products, and the willingness to use them, must be built on a foundation of participatory engagement throughout the research process.

That level of confidence may be challenging to achieve, however, in a COVID-19 response too often characterized by xenophobia, economic and racial discrimination and a highly politicized “warp speed” research and development effort, in which community engagement has been inconsistently prioritized.

Equally critical to sustained and effective pandemic responses is the need to build resilient health systems that proactively address and dismantle structural determinants of health.

Now is the time to develop bold visions of what universal health coverage can and must look like to ensure that health systems are shored up, revamped and redesigned to provide equitable access to a range of health services. As the Protecting Global Gains project has demonstrated, countries with flexible, resilient health systems, and an inclination toward innovation, are weathering both HIV and COVID-19 better than others.

While it may seem paradoxical, it is essential that as the world responds to COVID-19, it must also sustain and expand investments in HIV, TB, and malaria through funding mechanisms including the US President’s Emergency Plan for AIDS Relief and The Global Fund to Fight AIDS, Tuberculosis and Malaria, which are crucial sources of health system innovation.

Despite unprecedented prevention research progress, a new report by the Joint United Nations Programme on HIV/AIDS shows that 1.7 million people were newly infected with HIV last year — more than three times the global target of no more than 500,000 new infections annually by 2020.

Effective responses to COVID-19 and HIV will require a comprehensive, integrated and sustained commitment. As COVID-19 rightly consumes much of the world’s attention and global health resources in the year ahead, maintaining a clear focus on HIV, other serious health issues, and the responsiveness and effectiveness of health systems overall remains critical.

This hopeful moment in HIV prevention highlights how much we can learn from experience and underscores the imperative to develop and support resilient health systems that can fight multiple pandemics at once.

Americans are dying. Politics cannot be allowed to slow vaccine roll out.

AVAC and Treatment Action Group (TAG) welcome today’s announcement that preliminary data from the efficacy trial of Moderna’s mRNA COVID-19 vaccine indicate a high-level of protection against COVID-19. This is much needed good news as the US and other countries continue to see dangerously rising rates of COVID-19. As our organizations expressed in a statement last week about the Pfizer mRNA vaccine news, caution is warranted in interpreting this preliminary information as we wait for additional data from Moderna and further actions from the US Food and Drug Administration (FDA) and other global regulatory authorities.

In light of these hopeful announcements, planning for distribution of both of these vaccines must be accelerated. In the US, that planning – and potentially the beginning of distribution – will span two presidential administrations. It is clear that on January 20, 2021, there will be a change in executive leadership, even while the election results have not been certified and the Trump campaign continues to baselessly contest the results through lawsuits in a number of states.

AVAC and TAG call on the Trump campaign and administration, senior elected officials in the Republican Party and the leadership of the Republican National Committee to put the lives of the American people ahead of politics and move to ensure that there is a smooth transition of power that focuses on transparency. The GOP must work hand in hand with the incoming Biden Administration to maximize the impact of the limited number of vaccine doses that are expected to be available late in 2020 and early 2021.

The Biden transition team has laid out plans for a comprehensive COVID response that give us hope that – especially with the deployment of highly effective vaccines where they are needed most – the pandemic may begin to be controlled in 2021. That work will be more effective and will save more American lives if the incoming administration has all possible information about stockpiles, distribution plans and other logistics along with the ability to meet with and work with current administration officials and state and local officials.

But there is also urgent work to be done by the current Congress and Administration. Deploying these vaccines will be one of the most ambitious public health undertakings in history. A comprehensive, fully-funded and nationally-directed deployment plan must be developed now to complement the billions of dollars invested and the time, talent and commitment of thousands of researchers and trial participants who gave us these results. Vaccine costs should reflect the significant contributions of public financing to their design and development. Congress must come together in a bipartisan way to ensure that the CDC and state and local health departments have the funding, technology, training and support needed to ensure that vaccines can be deployed as quickly as possible to reach the most at-risk populations, accompanied by appropriate, evidence-based and trusted public health information.

We have lost almost 250,000 Americans to this virus, and new infections are rising every day. It is past time to put American lives ahead of politics.

Bold, evidence-based activism and advocacy have shaped the HIV response for nearly 40 years. To help bring the same focus and power to COVID-19 vaccine advocacy, AVAC has developed the Advocate’s Guide to COVID-19 Vaccine Access.

Monday’s announcement that Pfizer/BioNTech’s mRNA COVID-19 vaccine showed high levels of effectiveness was great news. As AVAC and TAG said in a statement yesterday, it’s now key to confirm the data and, at the same time, to begin to plan for rapid, affordable and equitable access to this and other vaccines.

The Advocate’s Guide is a timely tool for building the movement to make this happen. It provides plain-language explanations of the necessary components for equitable access to help inform and support advocates. These critical elements include:

• Adequate funding to the financing mechanisms supporting access: International development agencies should prioritize funding the COVAX Advance Market Commitment (AMC) to secure vaccine access for low and middle income countries (LMICs).
• Equity in vaccine purchasing: Some wealthy countries are limiting the supply of vaccines available for LMICs by entering into direct agreements with vaccine developers to secure millions of doses for the exclusive use of their own citizens.
• Pricing at low or no cost to all who need it: Fair pricing depends on transparency, and product developers must disclose development costs—both their own investments as well as the amounts received from public sector sources.
• Equitable distribution: Distribution criteria must be clear, ethical, rights-based, and include metrics for ensuring vaccine access for prioritized populations.
• Resilient health systems: Health systems and supply chains require national investments to prepare for the deployment of approved vaccines.

Advocates can demand that public health and human rights govern the eventual distribution of COVID-19 vaccines, not profits or politics. Initiatives to advance equitable access are already underway, such as the The People’s Pandemic Prevention Plan (of which AVAC is a supporter), the People’s Vaccine Alliance and the recent TRIPS waiver submitted by India and South Africa.

AIDS activists have a long history of building strong, specific, audacious access campaigns. As COVID-19 work continues, we’ll need to use those muscles to fight for global equity for COVID vaccines. AVAC looks forward to working with allies, including through the COVID Advocates Advisory Board (CAAB), to articulate specific campaigns focused on investments, legislation and more. And you can use the Guide to begin mapping strategy, identifying targets, and informing the following advocacy actions:

• Review decisions that have been made or are under consideration where you live;
• Formulate demands that are most relevant to your work; and
• Find out who is working on access planning and how you can connect with them.

We look forward to hearing your feedback and to collaborating on advocacy for rapid, equitable access.