How to be #HIVvaccineaware this #HVAD2021

Today, May 18th, is HIV Vaccine Awareness Day (HVAD), and advocates are calling for policies, science and advocacy for HIV vaccines that leverage the lessons of the past year.

This HVAD, we are focused on how the COVID experience can speed the development AND delivery of vaccines for HIV, TB, malaria and other diseases. Below you’ll find a roundup of resources, from AVAC and others, providing context, key messages and other information on what the field has learned from COVID-19, the essential role of vaccines in global health, and what’s next in the search for an HIV vaccine.

Vaccines & Global Health in Perspective

In a commentary today in Bhekisisa, Fatima Hassan of Health Justice Initiative and AVAC’s Mitchell Warren outline Finding an HIV vaccine: Five lessons from the response to COVID-19.
Episode 1 of the new podcast from the International AIDS Society (IAS), HIV Unmuted takes listeners to the global HIV change-makers who have shaped the response and asks what must happen now to end the AIDS epidemic. This debut episode features the NIH’s Anthony Fauci, AVAC’s Maureen Luba, Udom Likhitwonnawut from Thailand’s National Community Advisory Board, and others.
In their piece, How HIV Vaccine Advocacy Can Leverage Lessons from COVID-19, USAID’s Ashley Lima and Margaret McCluskey draw on the experiences and perspective of CASPR partners and their agenda for vaccine advocacy in the midst of COVID.

AVAC’s HVAD Package
Check out AVAC’s key messages for this HVAD. Designed for easy communication, this resource outlines the six ways that the COVID experience can shape HIV vaccine advocacy moving forward. For social media, we hope our sample tiles and tweets will inspire action to keep audiences #HIVvaccineaware this #HVAD2021. Download tiles 1, 2, 3, 4, 5, 6. Get the basics with AVAC’s annually updated powerpoint tutorial on HIV vaccines; current and planned vaccine research with this table of clinical trials; and our infographics gallery allows you to search by prevention intervention. All of these resources and more are up at www.avac.org/hvad.

IAVI’s HVAD Resources
We encourage you to explore IAVI’s #HVAD2021 toolkit for the perspectives of scientists and community liaison teams, videos on the science and development of vaccines, and tiles and tweets supporting their HVAD campaign at #EyesOnTheTarget and more.

Updates from the Field

Earlier today, WACI Health and AfNHI hosted a webinar exploring the remarkable advances in HIV vaccine research and the promising concepts being studied today with Ntando Yola, of APHA-South Africa and the Desmond Tutu Health Foundation, and Nyaradzo Mgodi, clinical pathologist from the University of Zimbabwe. Look for a recording of the webinar here, along with recordings of two additional webinars: one co-hosted by IAVI and KANCO featuring leading researchers and advocates in East Africa and one co-hosted by IAVI and SANAC featuring leaders in South Africa.
On May 13th, AVAC hosted a webinar HIV Vaccines in the Midst of COVID. In this recording you’ll hear researchers and advocates discussing new vaccine technologies, delivery challenges, community engagement, and confidence in both vaccines and vaccine research.
In the latest episode of AVAC’s Px Pulse podcast, Dive into the AMP Trials, we unpack the results of the recent Antibody-Mediated Prevention (AMP) studies, which will inform the fields of antibodies-for-prevention, and HIV vaccine research.

We can make #HVAD2021 the turning point, when the full potential of vaccines becomes undeniable, and the world renews its commitment to the search for vaccines for HIV, TB and other diseases that continue to threaten so many people’s health and well-being.

On this HIV Vaccine Awareness Day, leveraging the lessons of COVID to advance an HIV vaccine

This HIV Vaccine Awareness Day—observed each year on May 18—takes place in a new era of vaccine science. Accelerated by the knowledge, technologies, networks and community engagement models developed for HIV, the search for COVID-19 vaccines produced extraordinary results in record time. COVID demonstrated that a global sense of urgency to end a pandemic can produce ample research money overnight, help pharmaceutical companies, academic institutions, and nonprofits overcome previously insurmountable barriers to collaboration, and shrink vaccine development and testing timelines from decades to months. And yet, the results of those innovations are not translating quickly or equitably enough to end this pandemic. Advances in scientific R&D can’t have impact without equally robust investment in and commitment to delivery.

AVAC’s theme for HVAD 2021 is “HIV Vaccine Research: Building on Lessons from COVID”. We are focused on how the COVID experience can speed the development AND delivery of vaccines for HIV, TB, malaria and other diseases. Visit our dedicated HVAD 2021 page for resources to help make sense of this unique moment in vaccine history, and to build a global vaccine advocacy agenda for the future. There you’ll find:

The 2021 HVAD toolkit:

Key Messages: Designed for easy communication, the HVAD 2021 messages outline the six ways that the COVID experience can shape HIV vaccine advocacy moving forward.
Social media tiles: Sample tiles and tweets to inspire action to keep audiences #HIVvaccineaware this #HVAD2021.
Updated HIV Vaccines 101 PowerPoint presentation.

The page also has links to:

A recording of yesterday’s webinar, HIV Vaccines in the Midst of COVID, featuring HIV vaccine researchers and advocates Barney Graham (NIH Vaccine Research Center), Definate Nhamo (PZAT), Linda-Gail Bekker (Desmond Tutu Health Foundation), Matthew Rose (Health GAP) and Pontiano Kaleebu (MRC/UVRI & LSHTM Uganda Research Unit), discussing new vaccine technologies, delivery challenges, community engagement, and confidence in both vaccines and vaccine research.
A new episode of our Px Pulse podcast, Dive into the AMP Trials, which helps explain the results of the recent Antibody-Mediated Prevention (AMP) study and what it could mean for HIV vaccines.
Clinical Trials Update – A table of past, current and planned vaccine trials.
Infographics gallery – Search by intervention—antibody-mediated prevention or HIV vaccine—for all the latest infographics.

The opportunities and challenges brought to light by COVID make this an HIV Vaccine Awareness Day like no other. This #HVAD2021, we must all become #HIVvaccineaware and ensure new vaccines get developed and delivered!

New Resources on AVAC.org and PrEPWatch

In this round-up of new AVAC resources you’ll find a wide range of new resources:

Understanding the Latest in HIV Prevention Research

HIV Vaccine Awareness Day is just around the corner—May 18th! In preparation, AVAC hosted a webinar, HIV Vaccines in the Midst of COVID, on Thursday, May 13.

An Advocates’ Primer on Long-Acting Injectable Cabotegravir for PrEP: In 2020, two large-scale efficacy trials, HPTN 083 & 084, found that a long-acting injectable form of cabotegravir as PrEP provided high levels of protection among people at risk of HIV. That’s truly exciting. There’s also a lot to learn and understand about next steps. What do the trial results explain, what still needs to be explored, and what do advocates think needs to happen next? Check out our primer for what’s known and what’s next for this emerging biomedical HIV prevention strategy.

A webinar: Long-Acting Injectable Cabotegravir for PrEP – Understanding the results and key areas for advocacy: AVAC’s May 3rd webinar on CAB-LA featured the researchers who led the studies on long-acting injectable PrEP, and advocates who are defining key issues for the introduction of CAB-LA.

Dive into the AMP Trials: In this episode of Px Pulse, AVACers Jeanne Baron and Daisy Ouya talk to leading bNAb researcher, IAVI’s Devin Sok; veteran HIV research advocate Mark Hubbard who served on AMP’s protocol team; and a senior member of the HVTN’s community engagement team, a chief explainer of the AMP trails, Gail Broder. Together they explore why these findings point to the need for combination antibodies, the need for a better understanding of the types of HIV that are circulating in a community, the complicated implications of a key lab test, the TZM-bl assay, and more.

Developments in the HIV Prevention Pipeline: PrEP, vaccines and more: Created by AVAC, EATG, PrEP in Europe, and PrEPster, this slide deck and recorded webinar offers community educators and advocates a concise summary of existing and future PrEP products, and a community-level perspective on strategic advocacy for PrEP access and uptake.

Watchdogging PEPFAR

PEPFAR Watch is a new online resource from a collaboration working to hold PEPFAR accountable to communities. The website features reports, news, and resources to support community-led monitoring, a core initiative for accountability in PEPFAR programs. You can also sign up to become members and gain access to webinars, PEPFAR quarterly data and more. The collaboration includes Health GAP, AVAC, TAG, the O’Neill Institute, MPact, the PLUS Coalition, amfAR, and CHANGE. It should be a one stop shop for all the information you need to monitor and influence PEPFAR Country Operational Plans. Find other supportive resources on AVAC’s page: Advocate for Access to High-Impact Prevention.

A Spotlight on Equity and Ethics

Make Your Voice Heard: Towards advancing racial equity & diversity in biomedical research: In response to a call from the NIH for proposals to advance racial equity, diversity, and inclusion within all facets of the biomedical research workforce, and expand research to eliminate or lessen health disparities and inequities, AVAC’s John Meade authored a blog on the major recommendations offered to the NIH from a coalition of 25 HIV research advocate organization.

How can research ethics committees help to strengthen stakeholder engagement in health research in South Africa? An evaluation of REC documents: This article, co-authored by our CASPR partners at South Africa’s HIV AIDS Vaccines Ethics Group (HAVEG) and AVAC’s Jess Salzwedel, and published in the South African Journal of Bioethics and Law, recommends research ethics committees (RECs) step up the focus on stakeholder engagement. Researchers working with REC’s should plan for robust stakeholder engagement and REC documentation should be harmonized to reflect this priority.

Advocacy for Vaccine Access

Breaking the Bottlenecks to COVID-19 Vaccine Access: Ensuring global access to COVID vaccines—and any health commodity—requires a multi-pronged effort to get the right policies in place. This new infographic identifies the multiple factors that contribute to bottlenecks in the global supply of #COVID19 vaccines and how to address them.

We hope these resources, which cut across issues facing the field, will empower your advocacy where change is both crucial and possible.

New Episode of Px Pulse! Dive into the AMP Trials

May 13 Webinar! HIV Vaccines in the Midst of COVID

HIV Vaccine Awareness Day is just around the corner—May 18th! In preparation, AVAC hosted a webinar, HIV Vaccines in the Midst of COVID, on Thursday, May 13.

Expert researchers and advocates discussed major issues and advances in HIV vaccine R&D and the impacts of COVID-19 on vaccine research and delivery. The conversation to explored the lessons learned to date and how they serve as a warning, a model, and a body of evidence on the need for accelerated vaccine development and comprehensive strategies for equitable global access.

The moderated panel discussion included Barney Graham of the NIH Vaccine Research Center, who helped develop the mRNA vaccine technology; Pontiano Kaleebu of the MRC/UVRI & LSHTM Uganda Research Unit who helps lead the PrEPVacc trial; Linda-Gail Bekker of the Desmond Tutu Health Foundation who is involved in cutting-edge HIV vaccine research and COVID vaccine delivery; and Matthew Rose of Health GAP and Definate Nhamo of PZAT who deal with the wide range of issues of confidence in vaccine research AND delivery.

We hope you’ll enjoy this rich conversation and prepare to make the most of your advocacy around HIV Vaccine Awareness Day on May 18. Click here for recording and slides.

AVAC will be offering additional tools in the days to come, including infographics, key messages, a social media toolkit and more. These resources will help you make the case that the fastest, but still-faltering vaccine effort in history has demonstrated both what can be done and what must be done better in the global response to pandemics. Keep an eye on this space for the latest!

Long-Acting Injectable Cabotegravir for PrEP: Understanding Results of HPTN 083 & 084 and key areas for advocacy

Join AVAC and partners for webinar on May 3 webinar, 10-11:30am EDT where you can engage with researchers who led the studies about this injectable PrEP strategy and advocates who are leading essential advocacy efforts around the introduction of CAB-LA. On the call, lead trial investigators Sinead Delany-Moretlwe from HPTN 084 and Raphy Landovitz from HPTN 083 will provide updates, and we’ll be joined by AVAC’s Emily Bass, Chiluyfa Kasanda from TALC in Zambia, Richard Lusimbo from Pan Africa ILGA, and Sibongile Maseko who is an independent consultant and women’s health advocate based in Eswatini. Register here.

Moving Ahead with Long-Acting PrEP: Webinar and updated resource on CAB-LA research and advocacy

Long-acting injectable cabotegravir (CAB-LA) for PrEP is causing buzz and raising opportunities and questions for prevention advocates. Whether you’ve got questions or want to know what the buzz is about, AVAC has you covered.

We’ve updated our comprehensive primer on CAB-LA: Advocates’ Primer on Long-Acting Injectable Cabotegravir for PrEP: Understanding the Initial Results of HPTN 083 and HPTN 084, and held a May 3 webinar, 10-11:30am EDT where you can listen to the researchers who led the studies about this injectable PrEP strategy and advocates who are leading essential advocacy efforts around the introduction of CAB-LA.

On the call, lead trial investigators Sinead Delany-Moretlwe from HPTN 084 and Raphy Landovitz from HPTN 083 provided updates, and we were joined by AVAC’s Emily Bass, Chiluyfa Kasanda from TALC in Zambia, Richard Lusimbo from Pan Africa ILGA, and Sibongile Maseko who is an independent consultant and women’s health advocate based in Eswatini.

Watch the recording and find the slides here.

As our new primer describes, CAB-LA injections every eight weeks provided high levels of protection against HIV in cisgender women, cisgender men who have sex with men and transgender women who have sex with men. That’s truly exciting. There’s also a lot to learn and understand about next steps. A small number of people who received on-time injections and went on to acquire HIV did not test “HIV-positive” on standard antibody-based HIV tests. An even smaller number acquired resistance to integrase inhibitors—the class that includes cabotegravir and dolutegravir. In addition to these crucial issues, it’s also important to focus on questions of access. For those who want an injectable PrEP strategy, CAB-LA needs to be accessible and affordable.

What do the trial results explain, what still needs to be explored, and what do advocates think needs to happen next? Check out the updated resource and register the webinar to engage with it all!

Make Your Voice Heard: Towards advancing racial equity & diversity in biomedical research

John W. Meade Jr. is AVAC’s Senior Manager for Policy and Kevin Fisher is AVAC’s Director of Policy, Data and Analytics.

In the US, April is National Minority Health Month, and April 11-17th is Black Maternal Health Week. It is well past time to focus on distinct health disparities among Black, Indigenous, and other people of color (BIPOC) and Latinx communities, especially given the CDC’s recent, welcome focus on health disparities and equity. For example, Black people make up 13-15 percent of the United States population but about 27 percent of COVID-19 cases in the US, and the COVID-19 mortality rate for Latinx people is 2.5 times higher than that of white people, just to name a few. These long-standing disparities are rooted in systemic and institutional racism and perpetuated through research, the programs that implement the fruit of research, and the way both are funded. The impact on the HIV field is pernicious. BIPOC and Latinx communities carry an outsized burden and are also excluded from contributing to the solutions. The field is deprived of the insights, knowledge, experiences, expertise, creativity and innovation of BIPOC and Latinx communities—a universe of potential that’s neglected and squandered.

The Biden Administration opened this year with a commitment to address four “converging crises” facing the country: the COVID-19 pandemic, economic recession, climate change, and racial discrimination and inequity. The first two crises are relatively new, but the last is a multi-generational plague crippling this nation. The slow progress toward racial equity and diversity in science, technology, engineering, and mathematics (STEM) research, and National Institutes of Health (NIH)-funded research has been the subject of many initiatives over the years. Yet a recent NIH-commissioned analysis makes clear that existing policies, procedures and practices continue to perpetuate racial disparities and biases in the grantmaking process. A Black researcher’s chance of winning NIH funding remains 10 percentage points lower than that of applications from white counterparts, and has a lower probability of being awarded the NIH R01 Type 1 funding that is critical to a scientific career, regardless of the investigator’s degree.

On March 1, 2021, as part of the UNITE initiative, the NIH released a Request for Information (RFI) on the approaches NIH can take to advance racial equity, diversity, and inclusion within all facets of the biomedical research workforce, and expand research to eliminate or lessen health disparities and inequities. Responses are due April 23.

A number of HIV organizations have responded to the RFI including AIDS United, the Black Gay Researcher Collective, the National Black Gay Men’s Advocacy Coalition and the Black Women’s HIV/AIDS Network. The Research Working Group (RWG) of the Federal AIDS Policy Partnership, which is a coalition of more than 60 national and local HIV/AIDS research advocates, patients, clinicians and scientists from across the country, including AVAC, has developed a response focused on how racial disparities/biases specifically impact HIV research. The RWG response, signed by over 25 US HIV organizations, can be found here and calls on NIH to:

i. Develop new and nurture existing partnerships or collaborations that NIH could leverage to enhance the NIH-funded biomedical research enterprise within BIPOC and Latinx communities.

Early in the COVID-19 pandemic, NIH provided Meharry Medical College, an Historically Black College based in Tennessee, with vital research and technical support to advance development of COVID-19 treatment and vaccines. Investments in research institutions such as Meharry can address barriers to accessing the complex NIH funding mechanism and conduct research that will benefit BIPOC and Latinx communities.

ii. Review and amend existing NIH policies, procedures, or practices that may perpetuate racial disparities/bias in application preparations/submissions, peer review, and funding.

NIH grant applications are notoriously difficult to navigate. BIPOC and Latinx researchers in particular have the “cards stacked” against them, often having limited support and ability to navigate a deeply entrenched, institutionalized and competitive system. More BIPOC and Latinx researchers can be recruited by offering application assistance, this can include streamlined guidance and mentorship from institutions with a track record of successful applications.

iii. Increase support for researchers and research institutions based in Africa.

Given the scale of the HIV/AIDS epidemic in Africa, it is critical to develop regional capacity to conduct research on strategies that will improve HIV prevention and care in countries in Africa most impacted by HIV/AIDS.

iv. Diversify HIV clinical trial participant populations.

The NIH is mandated to ensure the inclusion of significant numbers of women and minority populations in all NIH-funded clinical research to the extent that it is appropriate to the scientific study. The HIV Prevention Trials Network (HPTN) 083 study has been a notable success in reaching very ambitious recruitment and retention targets for highly marginalized communities of color. Building partnerships with community and collaborative engagement to identify problems and develop solutions made this success possible.

v. Incentivize BIPOC and Latinx individuals to become STEM scientists and infectious disease physicians and researchers.

The US government, including agencies such as the Department of Education, must invest in STEM and diversity programs to engage BIPOC and Latinx students from an early age, and address financial and structural barriers that may deter BIPOC and Latinx students from entering the fields of medicine and science.

The NIH must hear responses to their RFI from not only BIPOC and Latinx researchers, but from anyone committed to improving the ways in which HIV research is funded through the NIH. Responses are due April 23 and can be submitted here.

Join us and share your thoughts and feedback with the NIH on how to advance racial equity in biomedical research.

Protecting Global Gains: Abiyamo Alayo: Happy Mother radio show takes community outreach further

The latest edition of Protecting Global Gains, Abiyamo Alayo: Happy Mother Radio Show Takes Community Outreach Further, describes how “mentor mothers” in Nigeria adapted to keep medicines and supplies flowing despite COVID-19 disruptions. Prior to COVID-19, over 100 mentor mothers, trained and supported by PLAN Foundation, were helping build healthy communities in Nigeria. Through direct community outreach, these mentors helped educate people about vital health issues and connected them to HIV testing, family planning, antenatal care, and more. When COVID-19 struck and lockdowns were enforced, this in-person outreach was halted and fears of unwanted pregnancies and disruptions to HIV/AIDS programming began to mount.

To respond to immediate needs, some mentor mothers quickly mobilized to become community-based distributors, delivering HIV medications and other essential supplies, including contraceptives, directly to their clients’ doorsteps. Then came Happy Mother / Abiyamo Alayo, a weekly hour-long bilingual (Yoruba and English) radio show offering a platform for mentor mothers and community health workers to promote understanding of women’s health and to directly address any listener questions. The work did not stop there: listeners to the radio show who expressed concerns about their health were connected to their closest mentor mother for personalized assistance.

Happy Mother / Abiyamo Alayo has been a hit, reaching communities far beyond the area where mentor mothers operated prior to COVID. The program’s success highlights the importance of client-centered services that connect community health and clinical care for maximum impact.

Follow Protecting Global Gains on social media at @hivpxresearch, @theglobalfight, @Amref_Worldwide, and #ProtectingGlobalGains, and consider amplifying these stories on your own social media. Advocates can also explore recommendations from the Frontline Community Health Workers Coalition and do their part to support the vital work of community health workers. Visit www.protectingglobalgains.org to learn more about how to take action.

Can Unprecedented Success in COVID Vaccine Development Boost Prospects for an HIV Vaccine?

Mitchell Warren is AVAC’s Executive Director. This piece first appeared on Science Speaks.

In February 2020, just as the COVID pandemic began its rapid global spread, a major HIV vaccine trial called HVTN 702, or Uhambo, was halted for lack of efficacy. Researchers and advocates had high hopes for Uhambo, building as it did on the RV144 trial, which provided the first evidence that an HIV vaccine could create a partially protective immune response. But Uhambo, like several studies before it, ended in disappointment.

On the same day that Uhambo ended, efforts to develop a vaccine against COVID-19, a disease that much of the world had yet to even hear about, were rapidly taking shape. In less than a year, the unprecedented global response to COVID produced multiple, highly effective vaccines. Yet the Uhambo researchers, in publishing their results last week in the New England Journal of Medicine, were obliged to remind the world that, nearly 40 years after the identification of HIV, there is still no AIDS vaccine:

“The high HIV-1 incidence that we observed in our trial illustrates the unrelenting aspect of the epidemic, especially among young women,” they wrote. “More than ever, an effective vaccine to prevent HIV-1 acquisition in diverse populations is needed.”

The Uhambo researchers are right: the need for an HIV vaccine could not be clearer. And the COVID-19 experience provides an important new roadmap for how to get one.

First, it’s critical to acknowledge that COVID vaccines exist because of decades of investments and advances in HIV vaccine research. HIV vaccine researchers and research networks led the scientific effort; HIV funding networks, scientific collaborations and clinical trial infrastructure sped COVID vaccine development; years of effort by HIV researchers to understand human immune responses guided the effort; vaccine platforms such as mRNA and Adeno26, developed and advanced through HIV vaccine studies, were repurposed for COVID prevention; and community advocates provided the expertise that helped enroll massive clinical trials and guide COVID vaccines through global regulatory processes.

So why do we have several effective COVID vaccines today, and none for HIV?

The clearest, most direct answer is that the scientific challenge of developing an HIV vaccine is much greater than it was for COVID. SARS CoV-2 is a relatively simple virus. HIV’s rapid mutations and capacity to evade natural immunity make it the most complex viral target ever encountered.

While the scientific challenges of HIV vaccine research are clear, however, so too is ample evidence from the COVID experience of what is possible. Simply put, the world is better positioned today than ever before to develop an HIV vaccine — if the HIV research effort can build on the COVID experience the way that COVID built on HIV.

Step one: we need a global effort to replicate the unprecedented level of funding, coordination, scientific collaboration and global political will that guided the fast-track development of COVID vaccines. With COVID, billions of dollars in research funding materialized overnight. Academic researchers, pharmaceutical executives and political leaders made the vaccine a priority, identifying and addressing obstacles to success in real-time. The result: there have been more large-scale COVID efficacy trials in one year than in more than 30 years of HIV vaccine research.

Next, financial investments were committed in advance of scientific answers, accelerating every stage of the COVID vaccine research process and condensing the gaps between each critical step from years to days. By contrast, it took seven years from getting the results of the RV144 trial before HVTN 702 even began.

Then, HIV vaccine research must move more rapidly to incorporate the latest scientific discoveries — from the COVID vaccine effort, and from other fields of study.

The cutting-edge mRNA technology used in several successful COVID vaccines, for example, holds great promise for HIV vaccine research. At the recent Conference on Retroviruses and Opportunistic Infections, the US National Institutes of Health and Moderna scientists presented initial data that an mRNA vaccine protected monkeys against HIV-like virus.

Two large studies of the Janssen Adeno26 HIV vaccine candidate, using another platform that was successfully employed against COVID, are also underway. When they report results, the field must be prepared to act on those findings with the same urgency, as well as the political and financial will that defined the COVID vaccine effort.

Studies that do not produce new prevention products, such as HVTN 702 and the recent Antibody Mediated Prevention (AMP) trial, can also offer critical insights into the type of immune responses that can provide durable protection against HIV, and can feed critically important data into a faster, more dynamic HIV vaccine effort.

Finally, planning for success must be the new normal. In this respect, the HIV vaccine effort can learn from COVID’s failures as well as its successes. Products don’t end epidemics; programs that deliver equitably and at scale do.

The infrastructure and urgency to manufacture and distribute COVID vaccines to translate great science into actual public health impact for all continues to lag tragically far behind research efforts, creating a bumpy rollout, vaccine shortages and significant equity issues. Avoiding the same mistakes for HIV will require expanding and sustaining current investments in vaccine manufacturing and distribution, and strengthening efforts to ensure that community leaders are integrally involved in efforts to introduce and ensure access to successful HIV vaccines.

The persistently high rates of new HIV infections among participants in the Uhambo and AMP studies are stark reminders that developing an HIV vaccine is critical. The COVID vaccine experience provides critical, real-world examples of how to get it done.

Understanding the Latest in HIV Prevention Research

Watchdogging PEPFAR

A Spotlight on Equity and Ethics

Advocacy for Vaccine Access

Stay up-to-date!