Pharmacokinetics and Pharmacodynamics: A primer for HIV Prevention Advocates

An informational sheet on how the safety of drugs are determined. This fact sheet explains two common terms used during the research process.

The Tipping Point

One way to measure progress in fighting AIDS is to compare the number of new HIV infections with the increase in HIV positive people on antiretroviral therapy (ART) over a given time period. An AIDS epidemic reaches its “tipping point” when the number of annual new HIV infection falls below the annual increase in patients starting ART. Coverage matters. A first milestone is treating approximately two thirds of people in need in a given country. Once that level is reached, countries and advocates can track progress to the tipping point.

From Research to Reality: Investing in HIV Prevention Research in a Challenging Landscape

The Vaccines Microbicides Resource Tracking Working Group, comprised of AVAC, the International AIDS Vaccine Initiative (IAVI), and the Joint United Nations Programme on HIV/AIDS (UNAIDS), uses a comprehensive methodology to track annual research and development investment trends in biomedical HIV prevention.

Ending AIDS Gamechangers

From the Ending AIDS report, a joint partnership between AVAC and amfAR. Visit www.endingaids.org for more information.

Trial Participants as Research Investors

ARV-Based Prevention Research and Development Product Pipeline

The Px Wire centerspread from April-June 2013 Volume 6, No. 2 showcases the ARV-based HIV prevention pipeline from pre-clinical research to implementation projects.

Achieving the End: One Year and Counting

In AVAC Report 2012, Achieving the End: One Year and Counting we’ve identified five priorities for action.

Microbicide Clinical Trial Participants by Region

This graphic from AVAC’s Microbicides by the Numbers one-pager shows the prominent role played by African trial participants in microbicide research.

The Importance of Location and Population to the HIV Response

This graphic from AVAC’s Microbicides by the Numbers one-pager shows on which populations the burden of the epidemic falls in different regions.

Global Prevention Research Advocacy Partnerships

This map from the AVAC Report 2012 identifies global prevention research advocacy partnerships.