VMMC (VMMC) Device Evaluations

There is a range of evaluation studies underway to learn more about how non-surgical devices can be used for adult male circumcision. This map from AVAC illustrates enrolling, ongoing or recently completed VMMC (VMMC) device evaluations as of 2013.

The HIV Prevention Research-to-Rollout Continuum

AVAC Playbook 2013–2014: Global goals and priorities

The AVAC’s Playbook is a concise look at global goals related to ten areas that are critical to ending the AIDS epidemic. The squares contain long-term goals; in the circles we have laid out priorities for 2014. Working with our partners, we develop and implement advocacy strategies to get us closer to these goals.

ARV-Based Prevention Pipeline (December 2013)

AIDS Vaccine Research: An overview (2013)

Use of Injectable Contraceptives and HIV Acquisition: The data to-date

Planned PrEP Demonstration Projects in Resource-Poor Settings

Clinical Trial Evidence for Oral and Topical Tenofovir-Based Prevention

2013 AVAC Report: Research and Reality [Executive Summary]

This year’s AVAC Report is about the new realities of biomedical HIV prevention research. In the last few years we’ve seen major advances, but also have had sobering realizations about the difficulties of developing new HIV prevention options that can succeed both in trials and programs in the real world. Landmark vaccine, microbicide and PrEP trial results energized the biomedical HIV prevention field. Yet, follow-up work from all these trials has been slower than necessary. In the search for new prevention tools for women two recent trials have found very low rates of adherence. These trials have given rise to important questions, not only about women’s willingness to use the test product, but about the research process itself.

We argue that the field needs to take a fast, focused look at fundamental assumptions and missed opportunities across the HIV prevention research field—and retool its approaches so that the next generation of research delivers advances that women and men want and will use.

ARV-Based Prevention Research and Development Product Pipeline: A Research Timeline

This timeline shows efficacy trials, related confirmatory studies and dates of possible regulatory submission for a range of ARV-based prevention options.