Global Investment in HIV Cure Research & Development in 2021

A decade of progress

MTN 035 (DESIRE)

HVTN 704/HPTN 085 (The AMP Study)

DISCOVER

PURPOSE 2

Impower 024

EBONI

Enhancing HIV Prevention with Injectable Preexposure Prophylaxis

Quarraisha Abdool Karim, Ph.D. writes about the results of HPTN 083 and the implications of long-acting injectable of PrEP with cabotegravir in the New England Journal of Medicine.

Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women

The results of HPTN 083, a trial evaluating the safety and efficacy of the injectable drug cabotegravir (CAB LA), for pre-exposure prophylaxis (PrEP) in HIV-uninfected cisgender men and transgender women who have sex with men (MSM and TGW), in the New England Journal of Medicine.

CAB-LA is a Highly Effective HIV Prevention Option; Now what?

Long-acting injectable cabotegravir (CAB-LA) is a promising new option for HIV prevention. In 2020, early results from two trials—HPTN 083 and HPTN 084—showed CAB-LA was safe and highly effective at preventing HIV when compared to daily oral TDF/FTC (Truvada) in men who have sex with men (MSM), transgender (TG) women and cisgender women. Now what? What questions remain unanswered and what support is needed now to make the growing range of prevention options feasible choices for people who may want and need them?