We know that an AIDS vaccine is possible and that a vaccine will be an important part of a long-term strategy to end the AIDS epidemic. The road ahead is long, but clinical trials—even those with disappointing results—and early-stage research provide critical clues to the way forward.
New HIV Infections by Region (2014)
Epidemics Successfully Combated with Vaccines (From 1980)
We know that an Vaccines will be an important part of a long-term strategy to end the HIV/AIDS epidemic. The road ahead is long, but a vaccines is possible. Clinical trials—even those with disappointing results—and early-stage research provide critical clues to the way forward.
Global Investment in Vaccines R&D (2014)
We know that an AIDS vaccine is possible and that a vaccine will be an important part of a long-term strategy to end the AIDS epidemic. The road ahead is long, but clinical trials—even those with disappointing results—and early-stage research provide critical clues to the way forward.
HIV Vaccine Research: An Update
A quick, colorful and comprehensive overview of HIV vaccine research. Four pages, five top-line updates, this is a speedy read, designed to give a sense of the momentum and major issues coming up in the year to come.
Vaccines in Vivo: Advances in AIDS Vaccine Research
On May 18, advocates around the world observed HIV Vaccine Awareness Day (HVAD)—an annual commemoration of the need for and commitment to the ongoing search for a vaccine. AVAC convened a webinar—Vaccines in Vivo: Advances in AIDS Vaccine Research—and updated a number of materials, including our “HVAD Toolkit” for those interested in easy-to-digest research updates. This year brought the launch of long-awaited initiation of clinical trials building on positive results from the RV144 “Thai” trial. This effort is led by the Pox-Protein Public-Private Partnership (P5), including the HIV Vaccine Trials Network, who joined the webinar to provide a status update of their current vaccine research and development program. We also featured Janssen, part of Johnson & Johnson, to provide an overview of the research program they are moving forward that focuses on a cross-clade vaccine product.
Vaccine Research: An overview
This graphic shows the big picture of AIDS vaccine concepts and clinical trials in process and on the horizon. It is an internationally simplified representation of a complex field. Some approaches are not listed, and related arenas like and cure research are omitted.
Additional Vaccine Approaches
A range of vaccine approaches are being tested in early phase clinical trials. This table provides highlights of this area of vaccine research.
Neutralizing Antibodies
This graphic explains on how neutralizing antibodies work, provides research background and gives an advocates’ checklist for what to look for going forward.
Vaccine Research Developing Programs
This graphic provides a state of the field on vaccine research development programs, giving details on the Pox-Protein Public-Private Partnership trials testing canarypox-protein based vaccine candidates and the Jannssen development program of Ad26 vector + Mosaic immunogen vaccine strategy.
AIDS Vaccine Science: Hot Seat
This is training exercise designed to bring HIV vaccine research information to life.