South Africa’s Trial Sites: An overview of HIV prevention research and demonstration sites in 2017, by location and intervention.
South African HIV Prevention Research and Demonstration Sites
Evolving Context for HIV Prevention Research (Map)
A global map showing selected HIV prevention research and oral PrEP status.
Global HIV Prevention R&D Investment by Technology Category, 2000-2016
In 2016, funding for HIV prevention R&D decreased by 3 percent (US$35 million) from the previous year, falling to US$1.17 billion. Funding in 2016 signals the lowest annual investment in HIV prevention R&D in more than a decade.
Composition of the Global HIV Prevention R&D Investment Base, 2015-2016
The call for a more diverse base of funders in the prevention R&D landscape is not a new one, but recent trends display greater polarization and a more extreme funding imbalance. In 2016, 75 percent of the overall funding came from the US public sector. Together, the US public sector and the BMGF represented 88 percent of the total global investment in 2016, compared to 81 percent in 2015.
Excerpted from our HIV prevention research tracking report, visit here for all graphics from the report.
HIV Prevention R&D Trial Participants by Region, 2016
HIV prevention research cannot be conducted without those who volunteer to participate in clinical trials or without the engagement of communities in which those trials take place. In 2016, there were almost 700,000 participants in HIV prevention research trials, primarily based in sites with high HIV/AIDS burdens in Africa, Asia, Latin America and the US.
Excerpted from our HIV prevention research tracking report, visit here for all graphics from the report.
From Proof-of-Concept to Prevention Phenomenon in Five Years
This timeline, first appearing in AVAC Report 2014/15: HIV Prevention on the Line, shows PrEP going from proof-of-concept to prevention phenomenon in five years and can be used to anticipate and speed action on the next generation of ARV-based prevention options.
Layers of Biomedical HIV Prevention Trial Stakeholders
Various stakeholders may influence or be affected by a biomedical HIV prevention trial. Stakeholders include trial participants and other community stakeholders as well as a broader range of national and international stakeholders.
Excerpted from the Good Participatory Practice (GPP) Guidelines, which provide trial funders, sponsors, and implementers with systematic guidance on how to effectively engage with all stakeholders in the design and conduct of biomedical HIV prevention trials. More at avac.org/gpp.
Financing the Search: Then and now
Funding for vaccines research in 1997 and 2016, segmented by government and other sector spending.
Number of Vaccines Trials: Then and now
A snapshot of the number of vaccine trials conducted globally between 1997 and 2017.
HIV-Specific Neutralizing Antibodies: A guide to targets and candidates
A detailed graphic describing the status of pre-clinical and clinical work around relevant bNAbs today.