A resource to support advocacy for multipurpose prevention technologies (MPTs). The Guide calls out four areas ripe for advocate involvement. It also provides a snapshot on the status of MPT research and development and data on investments—critical information that can support evidence-based advocacy.
Advocates’ Guide to Multipurpose Prevention Technologies
Updated Recommendations on HIV Prevention, Infant Diagnosis, Antiretroviral Initiation And Monitoring
A 2021 update to the WHO recommendations on HIV clinical and service delivery of prevention and treatment.
Internal Condoms: A Tool To Advance Sexual and Reproductive Health and Rights for All
Internal condoms, previously called female condoms, are an important tool to advance sexual and reproductive health and rights (SRHR) for all. Internal condoms are currently the only non-hormonal multipurpose prevention method designed for and initiated by women and receptive sexual partners that provides effective protection against unintended pregnancy and STI acquisition, including HIV. This resource shares new data on the efficacy and importance of internal condoms, and includes critical new USAID condom procurement data that indicate the need for increased internal condom procurement by United States global health agencies and programs.
Ethical considerations in HIV prevention trials
UNAIDS and the World Health Organization have published this updated guidance on ethical considerations in HIV prevention trials. The new guidance is the result of a year-long process that saw more than 80 experts and members of the public give inputs and is published 21 years after the first edition appeared.
How Can We End the Tuberculosis Epidemic? Lessons from Around the World
Anyone can get TB. In 2019, an estimated 10 million people contracted TB and more than 1.4 million died. Despite the numbers, we know we can end the TB epidemic. It is a matter of scaling up effective programs, dedicating sufficient resources and mobilizing the political will. This report highlights six locations where communities made impressive progress to significantly reduce TB cases and deaths – from California in the United States to Tomsk, Russia and Karachi, Pakistan.
Breaking the cycle of transmission: A human-centered approach to increase adoption and sustained use of HIV prevention among high-risk adolescent girls and young women (AGYW) in South Africa
Download findings from Breaking the Cycle of Transmission, a research effort to better understand AGYW decisions and behaviors related to HIV prevention; identify different segments to better tailor outreach; and how to reach each segment more effectively. The project uses user-centered research and human-centered design and piloting.
The HIV Prevention Market Manager (PMM), co-led by AVAC and CHAI and funded by the Bill & Melinda Gates Foundation, leads the research in partnership with behavioral research firm Final Mile, user-centered design firm Upstream Innovation and market research group Ask AfriKa, with the Surgo Foundation providing strategic guidance.
Evaluating, Scaling up and Enhancing Strategies for Supporting PrEP Continuation and Effective Use
In June 2019, the Prevention Product Manager (PMM)—a joint partnership between AVAC and the Clinton Health Access Initiative (CHAI)—and Jhpiego convened a think tank to consider how best to define and measure PrEP continuation. Its recommendations included modifying current PrEP indicators, recognizing that a single definition of correct or effective use might not be possible given fluctuating and variable HIV risk.
A second think tank was held in September 2020 with the theme Evaluating, Enhancing and Scaling up Strategies for Supporting PrEP Continuation and Effective Use. This think tank explored effective and promising strategies for helping people to stay on PrEP, strategies that can be scaled up across populations and locations.
Understanding the EMA Opinion and Next Steps for the Dapivirine Vaginal Ring
On July 24, 2020, the European Medicines Agency (EMA) announced a positive regulatory opinion from on the Dapivirine Vaginal Ring as an HIV prevention option for cisgender women age 18 and older. This document helps advocates to understand the steps that can and must be taken now that the EMA has provided its opinion. Read it here.
Global Investment in HIV Cure Research and Development in 2019
In 2014, the HIV Vaccines and Microbicides Resource Tracking Working Group and AVAC began a
Regulatory Approval Primer for Vaccine Advocates
The difference between speed and cutting corners can be one of life or death for individuals, and of impact versus impasse for societies. Advancing a vaccine candidate without peer-reviewed research results and thorough regulatory review can also undermine confidence in public institutions and vaccines generally. Global health advocates have an essential role to play as watchdogs of the regulatory systems that have worked well for decades, but may be vulnerable to global pressure for a vaccine and the current politicization of science.