PEP Needs Some Pep! Addressing PEP Neglect in HIV Prevention Research, Programming and Uptake

Thursday, November 3, 2022

During this webinar, experts and advocates addressed why PEP has been long neglected in HIV prevention research, programming, and uptake.

Featuring Dr. James Ayieko, Dr. Julie Fox, Dr. Ken Mayer, Dr, Catherine Koss, Njambi Njuguna and Ace Robinson

Recording / Slides / Resources

Cost of Goods Sold (COGS) Analyses

FAQ Debrief

This FAQ explains the use of Cost of Good Sold Analyses (COGS) and how they inform planning for product introduction.

RINGing the Bell for Choice: Actions and Solutions on Dapivirine Ring Access

Thursday, September 22, 2022

Hear the latest updates from African advocates leading the advocacy for access to the dapivirine ring. Plus tune in for the Population Council’s plans for moving the ring forward on multiple fronts, from roll-out of the monthly ring to research around the 3-month ring and multipurpose ring.

Recording / Slides / Resources

Px Wire April-June 2022, Vol. 12, No. 1

Newly relaunched, PxWire is AVAC’s quarterly update covering the latest in the field of biomedical HIV prevention research and development, implementation and advocacy. Download for a quick look at where we are in HIV prevention.

A Plan for Accelerating Access and Introduction of Injectable CAB for PrEP (Summary)

AVAC published Translating Scientific Advance into Public Health Impact: A Plan for Accelerating Access and Introduction of Injectable CAB for PrEP to provide a comprehensive view of all the moving parts and identify specific priority actions and actors responsible for ensuring time is not wasted and opportunity not squandered in introducing injectable cabotegravir for PrEP. ViiV, policy makers, normative agencies, donors, program implementers, researchers, generic manufacturers, civil society, advocates and communities each have critical roles to play in the coming months, and this summary provides an overview of the plan.

AVAC Comments to FDA in Support of PrEP Approval

Comments delivered to the FDA’s Antiviral Drugs Advisory Committee (AVDAC) Meeting by Mitchell Warren, Executive Director, AVAC.

Translating Scientific Advance into Public Health Impact

A Plan for Accelerating Access and Introduction of Injectable CAB for PrEP

AVAC’s Plan for Accelerating Access and Introduction of Injectable CAB for PrEP provides a comprehensive view of all the moving parts involved in delivering this new PrEP option and identifies priorities for ensuring time is not wasted and opportunity is not squandered. The plan focuses on learning the lessons from the first ten years of delivering oral PrEP and how to move faster, more strategically, and with greater coordination to maximize the impact of injectable CAB for PrEP.

Statement on the Dapivirine Ring for Women: Call for Accelerated Global Access

This statement, from a coalition of advocates, applauds the WHO for its ongoing support and its 2021 recommendation of the dapivirine vaginal ring as an additional prevention option for women. The advocates call on funders, country governments and community leaders to sustain their support for the ring’s introduction and rollout in African countries where it is needed and for prompt regulatory reviews. And they call on HIV programs to integrate the ring, and collaborate with communities on the design of those programs.

Consultation with FP/SRH Stakeholders on the Dual Prevention Pill

This report summarizes and reports next steps from an AVAC and FP2030 convened consultation with family planning (FP) and sexual and reproductive health (SRH) stakeholders. The aim of the consultation was to understand stakeholders’ unique perspectives on the Dual Prevention Pill (DPP), a daily oral pill that prevents HIV and pregnancy. The consultation helped to elevate questions and issues to consider as DPP introduction plans are refined and that can also inform the development and delivery of future multi-purpose prevention technologies (MPTs).

What Matters Right Now for Rolling Out the Ring and Injectable PrEP?

The HIV field has two new approved prevention options waiting in the wings, the dapivirine vaginal ring and injectable cabotegravir as PrEP. Until now, daily oral PrEP, first approved in 2012, has been the only drug-based strategy for HIV prevention.

So here we are: research has shown safety and efficacy for both the ring and injectable cabotegravir. Now it’s time to take the next steps to deliver these options and translate advances in science into real impact on the epidemic.

At AVAC, we’ve been calling for coordinated planning to introduce and rollout new products, while expanding access to existing options. These efforts must learn from the mistakes of the past, especially lessons from rolling out oral PrEP.

In this episode of PxPulseLinda-Gail Bekker from South Africa’s Desmond Tutu Health Foundation and Lillian Mworeko from the International Community of Women Living with HIV East Africa (ICWEA) join host Jeanne Baron and AVAC’s Executive Director Mitchell Warren to discuss innovative models for scale-up and delivery. Taking the right steps now could mean HIV prevention options fulfill their life-saving, epidemic-ending potential, and to do so requires working faster and more efficiently than ever before.

We dive into what lessons the field has learned, what’s still off-track, and the steps advocates, policy makers, drug makers and funders should each take right now to turn efficacious options into effective choices.

Resources

Dapivirine Vaginal Ring
Cabotegravir
Ring and CAB