Additional Vaccine Approaches

A range of vaccine approaches are being tested in early phase clinical trials. This table provides highlights of this area of vaccine research.

Neutralizing Antibodies

This graphic explains on how neutralizing antibodies work, provides research background and gives an advocates’ checklist for what to look for going forward.

Vaccine Research Developing Programs

This graphic provides a state of the field on vaccine research development programs, giving details on the Pox-Protein Public-Private Partnership trials testing canarypox-protein based vaccine candidates and the Jannssen development program of Ad26 vector + Mosaic immunogen vaccine strategy.

AIDS Vaccine Science: Hot Seat

This is training exercise designed to bring HIV vaccine research information to life.

Selected Guide to Pipeline of Antibodies, Long-Acting ARVs and Vaccines

This graphic provides a quick primer on passive immunization with HIV-specific antibodies, long-acting antiretroviral injectables, and preventive vaccines, including a new, informative table reviewing the pipelines in research and development for all three research avenues.

Px Wire April-June 2015, Vol. 8, No. 2

Px Wire is AVAC’s quarterly update covering the latest in the field of biomedical HIV prevention research, implementation and advocacy. In this issue, you’ll find updates and how WHO is approaching broader guidance on oral PrEP and a closer look at passive immunization.

Our centerspread provides a quick primer on passive immunization with HIV-specific antibodies, long-acting antiretroviral injectables, and preventive vaccines, including a new, informative table reviewing the pipelines in research and development for all three research avenues.

AVAC Report 2014/15: HIV Prevention on the Line

In AVAC Report 2014/15: HIV Prevention on the Line, we take on the current state of global targets for the AIDS response, looking beyond pithy slogans to explore what’s in place and what’s not in terms of targets, resources and action to begin to end the AIDS epidemic. We also provide concise updates and calls to action on key prevention interventions including AIDS vaccines, voluntary medical male circumcision, microbicides, PrEP, and hormonal contraception use and HIV risk.

Intervention Update: Hormonal Contraception and HIV

Excerpted from AVAC Report: HIV Prevention on the Line, this update describes recent discussion and analysis in the search for answers as to whether hormonal contraceptives, including long-acting methods such as Depo-Provera (DPMA) and other injectable contraceptives and the implant, affect women’s risk of acquiring HIV.

Intervention Update: Voluntary Medical Male Circumcision

Excerpted from AVAC Report: HIV Prevention on the Line, this update cites the success of a previous VMMC target and suggests the current lack of a target moving forward will stifle continued progress.

Intervention Update: What’s Next for AIDS Vaccines and the P5 Partnership?

Excerpted from AVAC Report: HIV Prevention on the Line, this update details attempts to test vaccine strategy which showed promise in the RV144 trial.