AVAC and the SEARCH team were joined by Professor Moses Kamya of Makerere University to find out why the early results of the SEARCH Dynamic Choice study were some of the most exciting to come out of CROI in 2024.
Conducted in Kenya and Uganda, the study offered oral PrEP, PEP or injectable cabotegravir to both men and women, and an option to switch products. Prevention services were person-centered, including access to a clinician by phone at any time, clinic and community access to services, and counseling to develop personalized adherence plans. Coverage among study participants increased to 70% (compared to 13% in the standard of care), 28% of participants used two different products during the study, and the study arm ended with zero incidence of HIV compared to 1.8% in the control group. These numbers show why adding to the method mix expands the number of people who continue with prevention—even as their needs change.
The webinar consisted of a presentation by Professor Kamya, followed by a robust discussion about the role of choice in HIV prevention.
