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CROI 2025 Shows the Promise of Research at its Best

The science offered at CROI 2025 is a showcase of the great promise and importance of research. Innovation in long-acting PrEP could transform global health, new evidence to support on-demand PrEP among women, insights coming from cure research, and expanding efforts to confront an epidemic in STIs, if the field can unite behind the evidence and refuse to be defeated.

Rallying for HIV Prevention Amid Policy Attacks

Those gathered at the CROI 2025, which is ongoing in San Francisco through March 12, are taking stock of a grim new reality that will once again demand heroics of us all. Science is on our side but the HIV response is paralyzed by the new US government.

Court Decision Reinforces Constitutional Principles, But Does Not Relieve Humanitarian Crisis

A federal district court in Washington, DC, granted in part and denied in part a motion for a preliminary injunction in a lawsuit brought by AVAC and Journalism Development Network (JDN). The motion asked the court to allow humanitarian work to continue while the lawsuit challenging the administration’s foreign-assistance freeze moves forward.

Advancing Sexual and Reproductive Health and Rights: Moving forward post-the 2024 US Election

Join Us for CROI 2025

CROI opens under drastically altered circumstances, as the new US Administration’s assault on global health and research devastates the HIV response. Whether attending in person or not, we share ways to follow along and join in the discussion and debate.

Monday Payment Deadline Is a Step Towards Relief in Foreign Assistance Case

On behalf of plaintiffs AIDS Vaccine Advocacy Coalition and Journalism Development Network, Public Citizen attorneys appeared in court today to argue for a preliminary injunction against the Trump administration, to enable humanitarian work to continue while a lawsuit challenging the administration’s attempted termination of foreign assistance moves forward.

Global Health Watch: NIH Challenges, PEPFAR uncertainty & the battle over foreign aid

This week’s issue covers challenges confronting the US National Institutes of Health under the new administration, the uncertain future of PEPFAR, continued legal battles over the foreign aid freeze and urgent efforts in Africa to secure sustainable health funding amid drastic aid cuts.

Trials & Projects Halted by USAID Funding Suspension

The stop-work orders have disrupted USAID-supported HIV prevention research, halting critical investigations in vaccine and next-generation PrEP strategies.

Where We Are Now with LEN for PrEP

The chaos in foreign assistance programs (including discontinuation of major PrEP programs), cuts in staffing and new demands on donor commitments will make decisions on the procurement of LEN for PrEP more complex and uncertain.

HIV Incidence, Age 15-49

Looking backward and then into the future, this chart shows actual HIV rates alongside projected rates with and without current prevention strategies (PrEP, VMMC, and free condoms).