MTN 003D

Status:Completed
Phase:Other
Principal Investigator(s):Ariane van der Straten
Objective:*/ This study is primarily exploratory and is designed to both identify factors that may have affected participant adherence to study product in VOICE, and describe how sexual behaviors, such as anal sex, may have had an effect on product efficacy. As such there is no specific hypothesis that is being tested.    Results: While there was interest in a variety of potential PrEP product formulations, a majority of VOICE-D participants preferred long-acting methods. More research is needed to gain insight into end-users' product formulation preference to inform messaging and market  segmentation for different PrEP products and resources to invest in products that target populations are most interested in using.     Last updated May 15, 2021 */
Prevention Option(s):Microbicides, PrEP
Study Design:
Results: Stated product formulation preferences for HIV pre-exposure prophylaxis among women in the VOICE-D
Official Code: NCT02358616
Related Publications:
Condoms, Lubricants and Rectal Cleansing: Practices Associated with Heterosexual Penile-Anal Intercourse Amongst Participants in an HIV Prevention Trial in South Africa, Uganda and Zimbabwe
Sexual scripting of heterosexual penile-anal intercourse amongst participants in an HIV prevention trial in South Africa, Uganda and Zimbabwe
Understanding women's motivations to participate in MTN-003/VOICE, a phase 2b HIV prevention trial with low adherence
Trial Sponsors: MTN, NAIAID (DAIDS-ES: 11893), NICHD, NIH (5UM1AI068633), NIMH
Start Date
End Date
December 26, 2012
March 13, 2014
Enrollment:219
Age range: 18 Years ↔ 45 Years
Population:Cisgender Women