MTN 014
Status:Completed
Phase:I
Principal Investigator(s):Gonasagrie Nair
Objective:To compare local and systemic pharmacokinetics of tenofovir reduced-glycerin 1% gel after 2 weeks of daily rectal use and after 2 weeks of daily vaginal use.
Prevention Option(s):Microbicides
Study Design:Open label, Randomized
Arms and Assigned Interventions
DescriptionReformulated rectal 1% tenofovir gel
Mode of DeliveryGel
ARMsExperimental
DescriptionReformulated vaginal 1% tenofovir gel
Mode of DeliveryGel
ARMsExperimental
Official Code:
NCT01768962
Trial Sponsors:
CONRAD, MTN, NIAID, NIMH
Start Date
End Date
October 31, 2012
December 10, 2014
Enrollment:14
Age range:
21 Years ↔
45 Years
Population:Cisgender Women