Pre-Exposure Prophylaxis Acceptability & Readiness Assessments for Toronto Gay, Bisexual and Other Men Who Have Sex With Men-5 (PREP-5)

Phase:Open Label
Principal Investigator(s):Darrell Tan, MD FRCPC PhD
Objective:PREPARATORY-5 is Canada's first PrEP demonstration project, and will examine real-world PrEP implementation issues including acceptability, effectiveness, impact on sexually transmitted infections, and strategies for supporting adherence outside the clinical trial setting. The investigators have also established a comprehensive community-based research program investigating the role of community-based organizations in PrEP implementation and delivery.
Prevention Option(s):PrEP
Study Design:Open label
Arms and Assigned Interventions
DescriptionMSM receiving once daily TDF/FTC-based (Truvada®) pre-exposure prophylaxis.
Mode of Delivery
Official Code: NCT02149888
Trial Sponsors: AIDS Committee of Toronto, Canadian AIDS Treatment Information Exchange, Gilead Sciences, Maple Leaf Medical Clinic, Ryerson University, St. Michael's Hospital, Toronto Hassle Free Clinic
Start Date
End Date
October 1, 2014
June 19, 2016
Age range: 18 Years ↔ any
Population:Cisgender Men