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Where We Are Now with LEN for PrEP

The chaos in foreign assistance programs (including discontinuation of major PrEP programs), cuts in staffing and new demands on donor commitments will make decisions on the procurement of LEN for PrEP more complex and uncertain.

Prevention Option:

October 2025





New LEN Resources, Publications on PLP and TG Inclusion and More!

This roundup from AVAC highlights key developments across the field of HIV prevention from accelerating access to lenacapavir, to advancing inclusion of pregnant and lactating people, and trans and gender-diverse communities in research.

October 2025


Inclusion Made Simple, In Difficult Times 

This is not the time to scrub tran and gender diverse people inclusion from HIV trial designs and protocols. Now is the moment to use everything at our disposal to set in motion an era of HIV research that meaningfully responds to this community’s needs.

October 2025


AVAC Input for Recompetition of the NIAID HIV/AIDS Clinical Trials Networks

AVAC’s formal input submitted on the re-competition of the NIAID HIV/AIDS Clinical Trials Networks. The recommendations were informed by the People’s Research Agenda (PRA), a comprehensive framework developed through consultations with over 130 community representatives across 23 countries.

Prevention Option:

October 2025



Global Health Watch: US government shuts down, foreign aid funding expires, Jeanne Marrazzo fired from NIH, issue 36

The US government shutdown that began at midnight on October 1 has stalled key public health operations just as the Supreme Court issued a ruling in AVAC v. Department of State that allowed $4 billion dollars in foreign aid to expire, eroding both health and human services and constitutional checks and balances. Meanwhile, Jeanne Marrazzo was officially fired as Director of NIAID, underscoring how politically motivated attacks on science are dismantling the infrastructure that has underpinned decades of progress in HIV prevention and research.

Prevention Option:

October 2025


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