P-Values

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

At P-Values, you’ll find updates, perspective, insights and information from staff and partners working on the frontlines of research, advocacy and implementation. P-value is a statistical term for the probability that a trial result is reliable and not the outcome of chance. 

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Global Health Watch: Research in Peril, Ebola Vaccine Devs, Congress Questions Sec. Of State, Exec Order Makes Firing HHS Employees Easier

A new proposed White House OMB rule seeking greater political oversight of federal grantmaking puts research in peril; vaccine developments accelerate as the Ebola Bundibugyo outbreak grows; the US Secretary of State takes questions from multiple Congressional committees about the future of PEPFAR; responding to the Ebola outbreak; support of Gavi, the Vaccine Alliance; and US global health security.

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Blog Post

HIV Prevention Advocates Applaud South Africa’s Introduction of Lenacapavir for PrEP

In a landmark moment, South Africa today became the 9th African country to introduce lencapavir (LEN) for HIV prevention. South Africa’s introduction of LEN is especially significant given the country’s central role in shaping the regional HIV response and the global PrEP market. As the largest PrEP market in the world, South Africa’s leadership can help drive the demand, volume, market confidence and lower prices needed to accelerate equitable access across the continent and the world.

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Global Health Watch: Research in Peril, Ebola Vaccine Devs, Congress Questions Sec. Of State, Exec Order Makes Firing HHS Employees Easier

A new proposed White House OMB rule seeking greater political oversight of federal grantmaking puts research in peril; vaccine developments accelerate as the Ebola Bundibugyo outbreak grows; the US Secretary of State takes questions from multiple Congressional committees about the future of PEPFAR; responding to the Ebola outbreak; support of Gavi, the Vaccine Alliance; and US global health security.

June 2026

HIV Prevention Advocates Applaud South Africa’s Introduction of Lenacapavir for PrEP

In a landmark moment, South Africa today became the 9th African country to introduce lencapavir (LEN) for HIV prevention. South Africa’s introduction of LEN is especially significant given the country’s central role in shaping the regional HIV response and the global PrEP market. As the largest PrEP market in the world, South Africa’s leadership can help drive the demand, volume, market confidence and lower prices needed to accelerate equitable access across the continent and the world.

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June 2026

ACTION ALERT: Research in Peril

In an ongoing attempt to decimate and politicize science, the White House Office of Management and Budget proposed sweeping new regulations to significantly expand political interference in federal research funding decisions across all federal grants, threatening science, global health and the HIV/AIDS response.

June 2026

Lenacapavir Arrives in South Africa on Friday

Injectable lenacapavir for PrEP (LEN) is rolling out across Africa faster than any HIV prevention option to date. This Friday, South Africa will become the ninth African country to introduce LEN. Read for updated resources to track this progress and ensure the field moves with speed, scale and equity.

June 2026

Global Health Watch: CDC Directors Warn About PEPFAR, Ebola & Aid Cuts, Policy Developments Threaten Open Science

A commentary by eight former US CDC directors urges the US Department of State to reform PEPFAR, not dismantle it; the growing Ebola outbreak and ongoing hantavirus concerns underscore the risks abrupt changes pose to global health security; and a proposed new US federal grant regulation could significantly expand political influence over scientific funding decisions and research priorities.

May 2026

AI & HIV Newsletter

We are excited to release our first AI & HIV Newsletter! This new quarterly resource will provide advocates and the global community with the information and resources to engage with AI in ways that strengthen equity, protect individuals and communities and prioritize their inclusion, and ensure that technological innovation advances the HIV response rather than undermines it.

May 2026

INTEREST 2026

INTEREST 2026 took place from 12–15 May 2026, in Dar es Salaam, Tanzania. Read reflections and key takeaways from AVAC’s Grace Kumwenda and Access Bridge’s Wawira Nyagah.

May 2026

Global Health Watch: Ebola exposes gaps; WHA79 debates future of WHO; continued dismantling of US health leadership

The hantavirus outbreak and now emerging Ebola crisis are exposing major gaps in pandemic preparedness and global health cooperation; the future of the WHO, multilateralism and the HIV response is being debated at this week’s World Health Assembly; while the US government continues to deconstruct its public health leadership.

May 2026

The Impact Report

An effective HIV prevention response requires real-time evidence and leadership rooted in the lived experiences of the communities that are most impacted. This edition of The Impact Report highlights AVAC’s role in both how African leadership drives HIV prevention access and how PrEPWatch transforms data into action for PrEP access.

May 2026

PrEPWatch: Transforming Data into Action for PrEP Access

AVAC’s PrEPWatch is the trusted global repository for comprehensive, user-friendly and up-to-the-minute information about HIV prevention methods. The platform provides data, analysis, tools, and comprehensive resources that are widely used by governments, donors, and partners to inform HIV prevention policy, financing, and programmatic decisions.

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May 2026

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P-Values Blog

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

Advocates Network

AVAC’s email list for organization and individuals interested in timely updates and critical perspectives on developments in biomedical HIV prevention.

Weekly News Digest

A comprehensive round-up of HIV prevention media coverage and scientific publications.

PxPulse

Each month this podcast uses interviews, discussion and first-person reflections to explore vital topics confronting the field of HIV prevention research.

PxWire

PxWire is AVAC’s quarterly update on biomedical HIV prevention. Each issue highlights key developments, challenges and opportunities, and features a centerspread infographic that provides a visual tool for framing these issues.

Pandemic Watch

Pandemic Watch is a curated news digest on the latest pandemic prevention, preparedness, and response (PPPR) news and resources.

Press Releases

A collection of official statements from AVAC.

AVAC in the News

Media clippings featuring AVAC, its staff and close partners in the news media.