P-Values

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

At P-Values, you’ll find updates, perspective, insights and information from staff and partners working on the frontlines of research, advocacy and implementation. P-value is a statistical term for the probability that a trial result is reliable and not the outcome of chance. 

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Global Health Watch: Leadership Changes at US Health Agencies, Global Fund Replenishment and What’s Next for Vaccine Regulation

This week, we reflect on the escalating war on science. Two recent pieces illustrate how budget decisions and policy priorities are reshaping US scientific and global health leadership and undermining the stability of programs relied on by hundreds of millions of people. We also track the consolidation of power across US health agencies, mounting uncertainty in vaccine regulation, and the Global Fund’s ongoing replenishment.

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Global Health Watch: Leadership Changes at US Health Agencies, Global Fund Replenishment and What’s Next for Vaccine Regulation

This week, we reflect on the escalating war on science. Two recent pieces illustrate how budget decisions and policy priorities are reshaping US scientific and global health leadership and undermining the stability of programs relied on by hundreds of millions of people. We also track the consolidation of power across US health agencies, mounting uncertainty in vaccine regulation, and the Global Fund’s ongoing replenishment.

February 2026

AVAC’s Year in Review

In a year marked by funding freezes, political disruption and historic scientific breakthroughs, we are proud to share our 2025 Year in Review – one defined by crisis and resilience.

February 2026

CROI 2026: Resources and what to watch

AVAC will be tracking the HIV and STI science at CROI 2026, including advances in long-acting HIV prevention, evolving science around cure, and important discussions on the impact of the global funding crisis on research, development, and delivery. Here we share ways to follow and join in the conversation, in-person or virtually. 

February 2026

Global Health Watch: States Sue Over Public Health Funding, Vaccine Systems Strain, Advocates Press Merck on Equitable Access

It’s been one year since AVAC and the Global Health Council filed their lawsuits over the sweeping foreign assistance freeze — cases that challenged the Administration’s withholding of Congressionally appropriated funds. That broader dispute continues, as four US states sued the administration over its decision to withhold $600 million in public health grants. This issue also examines ongoing signs of erosion in vaccine confidence and calls for early global access planning for Merck’s monthly oral PrEP candidate.

February 2026

One year ago, we sued the US Government…

On the first day of the new administration, a sweeping foreign aid freeze shut down life-saving HIV and global health programs overnight. Over 52 weeks, AVAC documented the harm, and took the fight to court.

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February 2026

Global Health Watch: Foreign Affairs Bill Passes, Aid Cuts Projected to Cause Millions of Deaths by 2030, UN & WHO in Financial Crisis

This week a $50 billion US foreign affairs spending bill was signed into law, averting severe proposed cuts; a new modelling analysis projects millions of additional preventable deaths by 2030 if global aid cuts continue; and the financial crises facing the UN and WHO continue. We are also following plans to transition or close the Oregon National Primate Research Center, a leading research institution.

February 2026

Impact of US Withdrawal from WHO, New Data on PrEP, Cure Academy Applications Open

New this week: resources on the impact of harmful US policies on the HIV response; updated infographics on the ups and downs in PrEP; and an opportunity to apply for the US HIV Cure Academy in North Carolina this April.

February 2026

Global Health Watch: Budget stalled, Gag Rule expanded, US leaves WHO, AAP’s own immunization recommendations

As this issue goes to publication, the US fiscal year budget remains unresolved in the Senate, adding to uncertainty for global health funding. This week’s issue tracks the expansion of the Global Gag Rule, the US’s formal withdrawal from the WHO, growing pushback on concerning vaccine policy, and the new finding that nearly half of US CDC surveillance databases have been paused or stopped.

January 2026

Roundup: Must-Read Conversations and Resources from the Last Week 

Last week marked one year since the US president took office and began systematically dismantling global health and equity. Here is a roundup of essential conversations and resources summarizing the past 365 days and what’s at stake as we move forward.

January 2026

AVAC Calls for the Immediate Rejection of the Global Gag Rule and Any Expansion of it

AVAC calls for the immediate rejection of the Global Gag Rule and any expansion of it and urges US lawmakers to uphold science, human rights, and public health.

January 2026

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P-Values Blog

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

Advocates Network

AVAC’s email list for organization and individuals interested in timely updates and critical perspectives on developments in biomedical HIV prevention.

Weekly News Digest

A comprehensive round-up of HIV prevention media coverage and scientific publications.

PxPulse

Each month this podcast uses interviews, discussion and first-person reflections to explore vital topics confronting the field of HIV prevention research.

PxWire

PxWire is AVAC’s quarterly update on biomedical HIV prevention. Each issue highlights key developments, challenges and opportunities, and features a centerspread infographic that provides a visual tool for framing these issues.

Pandemic Watch

Pandemic Watch is a curated news digest on the latest pandemic prevention, preparedness, and response (PPPR) news and resources.

Press Releases

A collection of official statements from AVAC.

AVAC in the News

Media clippings featuring AVAC, its staff and close partners in the news media.