P-Values

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

At P-Values, you’ll find updates, perspective, insights and information from staff and partners working on the frontlines of research, advocacy and implementation. P-value is a statistical term for the probability that a trial result is reliable and not the outcome of chance. 

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Global Health Watch: LEN for PrEP commitments, US budget cuts shift from basic research, “trade over aid” raises global health concerns

This week, a new commitment to expand the reach of lenacapavir for HIV PrEP is a step forward but not enough to deliver impact, detail on the proposed US budget cuts reflects a shift away from basic research, and a broader shift toward “trade over aid” raises new concerns for global health financing and impact.

April 2026


Three Million is a Step Forward, But Not Enough

In response to the the US State Department, Global Fund, and Gilead announcement of increased volume commitments for lenacapavir (LEN) for HIV prevention, AVAC and Access Bridge call for global leaders to do even more to ensure meaningful, expanded access.

April 2026


Roundup: The latest resources powering HIV & STI advocacy

Advocates are driving progress in HIV and STI prevention—guiding research, expanding access, holding powerful actors accountable and elevating community priorities. This roundup highlights advocacy in action, from new resources and policy frameworks to updates on the rollout of the latest prevention tools.

April 2026


Global Health Watch: Proposed US budget cuts, HIV supply chain disruptions, Global Fund commitments, new attempt to weaken US vax policy

Proposed US budget cuts, HIV supply chain disruptions, evolving Global Fund commitments, and a renewed attempt to undermine US vaccine policies highlight a landscape under rapid shifts this week.

April 2026


AVAC and Partners Launch New STI Advocacy Agendas in Kenya, South Africa and Zimbabwe

AVAC and partners are proud to share three new national sexually transmitted infections (STIs) advocacy agendas for Kenya, South Africa and Zimbabwe, providing coordinated agendas to elevate STIs as a national health priority and accelerate actions on R&D and delivery of STI vaccines, diagnostics, prevention and care.

Prevention Option:

April 2026


Global Health Watch: Zambia’s Bilateral MoU, NIH Budget Cut, LEN Pricing & Access, New HIV Prevention Access Framework

This week, the global health world lost a true leader, Stephen Lewis, whose life was defined by an unwavering commitment to creating a better, more just world. Lewis’ unwavering passion and fearless advocacy continue to set the standard, reminding us that global health demands urgency, equity and accountability. This week’s issue follows that charge.

April 2026


Global Health Watch: Pandemic Treaty Tensions, Public Health Emergency, CDC Instability & Global Fund’s Role in Bilateral Health Deals

Pandemic treaty negotiations ahead of the World Health Assembly show rising tensions, as countries push for equity in pathogen sharing, alongside the expansion of US bilateral health deals and the evolving role of the Global Fund within this shifting architecture. This issue also covers calls to declare recent US global health policy shifts a Public Health Emergency of International Concern, deepening instability at the US CDC, and updates on US government bilateral agreements.

March 2026


The Impact Report

The Impact Report highlights the power of advocacy, research translation, and partnership to advance HIV prevention and global health equity. In this first edition — the introduction of LEN in Zambia, how AVAC and partners are standing up for science, and new efforts to translate evidence for decision making.

March 2026


Bridging the Gap Between Science and Communities

In a moment when access to clear, credible HIV science has never been more urgent, AVAC is bridging the gap between global research conferences and the communities who need that information most—through real-time webinars, digestible recaps, and resources trusted by leading researchers.

March 2026


Standing Up for Science

As the US administration threatens to dismantle decades of biomedical research progress, AVAC and partners have mounted a powerful defense—highlighted by the 24-Hour Marathon to Save AIDS Research, which united 75 presenters and reached more than 7,000 people across 28 countries.

March 2026


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P-Values Blog

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

Advocates Network

AVAC’s email list for organization and individuals interested in timely updates and critical perspectives on developments in biomedical HIV prevention.

Weekly News Digest

A comprehensive round-up of HIV prevention media coverage and scientific publications.

PxPulse

Each month this podcast uses interviews, discussion and first-person reflections to explore vital topics confronting the field of HIV prevention research.

PxWire

PxWire is AVAC’s quarterly update on biomedical HIV prevention. Each issue highlights key developments, challenges and opportunities, and features a centerspread infographic that provides a visual tool for framing these issues.

Pandemic Watch

Pandemic Watch is a curated news digest on the latest pandemic prevention, preparedness, and response (PPPR) news and resources.

Press Releases

A collection of official statements from AVAC.

AVAC in the News

Media clippings featuring AVAC, its staff and close partners in the news media.