P-Values

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

At P-Values, you’ll find updates, perspective, insights and information from staff and partners working on the frontlines of research, advocacy and implementation. P-value is a statistical term for the probability that a trial result is reliable and not the outcome of chance. 

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Global Health Watch: Fired Vaccine Experts; House Rescissions Votes; CDC Staff Called Back; NIH Scientists Speak Out

This week brought the unprecedented removal of the US vaccine advisory committee, layoff reversals and confusion at the US CDC and a public letter signed by over 1,000 NIH scientists denouncing the administration’s actions. And just as this week’s issue was going to press, the US House of Representatives passed the President’s request for a rescission of billions of dollars – primarily for foreign assistance. This week underscored the urgency of defending evidence-based health policy.

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Global Health Watch: Fired Vaccine Experts; House Rescissions Votes; CDC Staff Called Back; NIH Scientists Speak Out

This week brought the unprecedented removal of the US vaccine advisory committee, layoff reversals and confusion at the US CDC and a public letter signed by over 1,000 NIH scientists denouncing the administration’s actions. And just as this week’s issue was going to press, the US House of Representatives passed the President’s request for a rescission of billions of dollars – primarily for foreign assistance. This week underscored the urgency of defending evidence-based health policy.

June 2025

AVAC Condemns Removal of the Advisory Committee on Immunization Practices

AVAC strongly condemns Secretary of Health and Human Services, Robert F. Kennedy, Jr., for removing all members of the Advisory Committee on Immunization Practices (ACIP). This committee of vaccine experts—with decades of experience in vaccine development, delivery and safety—is responsible for developing the country’s vaccine policies and recommendations for the CDC.

June 2025

New Report: Getting PrEP Rollout Right This Time

Getting PrEP Rollout Right This Time: Lessons from the Field examines key insights from the rollout of oral PrEP and early introduction of injectable CAB and the dapivirine vaginal ring to inform a faster, smarter and more equitable introduction of future HIV prevention tools, including long-acting injectable PrEP, such as lenacapavir.

June 2025

Global Health Watch: Dismantling Decades of Progress, FY26 Proposed Budget and Rescissions Package and More

This week brought more devastating actions from the US administration, with serious consequences for global health. From a proposed rescissions package of the current year’s funding to deep cuts in the proposed Fiscal Year 2026 budget, the end of funding to the leading NIH-funded vaccine consortia, to proposed reductions to the Global Fund match and new immigration restrictions, the threats to health, science, global partnerships, research progress, and health equity are here.

June 2025

AVAC Denounces White House Effort to Codify DOGE Cuts to Health, Research and Foreign Assistance

AVAC denounces recent proposals and actions by the US administration that signal a clear intention to defund and eliminate lifesaving global health research, development and delivery programs. If passed by Congress, proposed funding rescissions for the current year’s budget would claw back billions of Congressionally appropriated dollars for critical, life-saving programs.

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June 2025

What It Took to Make LEN for PrEP Possible + What’s at Risk Now

The US presidential administration released its full US FY26 budget proposal, and it includes a series of devastating cuts that threaten to roll back HIV prevention efforts in the US and globally by decades. In a cruel irony, this proposal comes just as the field reaches a moment of historic promise in HIV prevention. Learn more on our webinar.

June 2025

Global Health Watch: Global Fund + Gavi, Musk exit, threats to NGO funding and more

This week we see new developments that could reshape global health financing and US policies on science and research, including the release of the full FY26 budget, which is expected later in the day. From a potential operational merger between the Global Fund and Gavi to more intense threats to NGO funding, foreign aid, and vaccine guidance, this issue shares the implications of rising political pressure.

May 2025

The US Legacy in HIV is Unraveling

If the administration is intent on unraveling America’s legacy in global health, Congress must veto that agenda. It must preserve PEPFAR’s integrity and the US’s commitment to the goal of ending HIV as a public health threat.

May 2025

Global Health Watch: WHA78, Misinformation at Congressional Hearings, Global Fund Cuts & More

The US Secretary of State and the Secretary of Health and Human Services appeared before Congress this week defending foreign aid cuts and the dismantling of USAID. Advocates are responding, including the Treatment Action Group (TAG) which issued a stark warning. Meanwhile, the US was absent from the World Health Assembly. All this plus looming Global Fund shortfalls, and new COVID-19 vaccine policy changes in this week’s issue.

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May 2025

HIV Vaccine Awareness Day 2025

HVAD 2025 comes as the US presidential administration is actively working to dismantle HIV research and demolish the architecture of global health. The entire HIV response — from basic research and clinical development to policy, programs, and global access to life-saving treatment and prevention — is now under attack, and the world runs the risk of reversing the strides made to end HIV.

May 2025

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P-Values Blog

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

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A collection of official statements from AVAC.

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