P-Values

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

At P-Values, you’ll find updates, perspective, insights and information from staff and partners working on the frontlines of research, advocacy and implementation. P-value is a statistical term for the probability that a trial result is reliable and not the outcome of chance. 

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Global Health Watch: WHA78, Misinformation at Congressional Hearings, Global Fund Cuts & More

The US Secretary of State and the Secretary of Health and Human Services appeared before Congress this week defending foreign aid cuts and the dismantling of USAID. Advocates are responding, including the Treatment Action Group (TAG) which issued a stark warning: US agencies are engaging in “unethical, dishonorable, and potentially law-breaking machinations” under new leadership, particularly at the NIH. Meanwhile, the US was absent from the World Health Assembly, where the WHO Pandemic Agreement was ratified and where a high-level dialogue on long-acting HIV prevention took place. All this plus looming Global Fund shortfalls, and new COVID-19 vaccine policy changes in this week’s issue.

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Global Health Watch: WHA78, Misinformation at Congressional Hearings, Global Fund Cuts & More

The US Secretary of State and the Secretary of Health and Human Services appeared before Congress this week defending foreign aid cuts and the dismantling of USAID. Advocates are responding, including the Treatment Action Group (TAG) which issued a stark warning: US agencies are engaging in “unethical, dishonorable, and potentially law-breaking machinations” under new leadership, particularly at the NIH. Meanwhile, the US was absent from the World Health Assembly, where the WHO Pandemic Agreement was ratified and where a high-level dialogue on long-acting HIV prevention took place. All this plus looming Global Fund shortfalls, and new COVID-19 vaccine policy changes in this week’s issue.

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May 2025

HIV Vaccine Awareness Day 2025

HVAD 2025 comes as the US presidential administration is actively working to dismantle HIV research and demolish the architecture of global health. The entire HIV response — from basic research and clinical development to policy, programs, and global access to life-saving treatment and prevention — is now under attack, and the world runs the risk of reversing the strides made to end HIV.

May 2025

Global Health Watch: FY26 Proposed Budget, WHO Leadership Changes and New AVAC Resources

This week’s issue covers the Secretary of Health and Human Services’ defense of deep NIH budget cuts before Congress, leadership changes at WHO, and the latest update in AVAC’s lawsuit attempting to halt the US foreign aid freeze.

May 2025

A Move to Entrench US Foreign Assistance Cuts & How to Fight Back

The US President’s proposed budget for next year includes sweeping cuts to the NIH, CDC, USAID and the elimination of vital global and minority health research programs. These cuts represent an effort to extend legally challenged cuts made by executive order earlier this year, and to codify them into law with congressional approval. If successful, they will result in the drastic cut of US federal investments in global health research, development and delivery.

May 2025

Global Health Watch: FY26 Proposed Budget Cuts, New FDA Leadership, WHO + UNAIDS and more

This week the proposed US 2026 budget was released by the White House and would slash funding across the entire federal government, gutting NIH and other agencies in the Department of Health and Human Services, and further reduce foreign assistance. In addition, a hostile critic of the US FDA is appointed to lead its Center for Biologics Evaluation and Research, which oversees vaccines amongst other things. Also, the UN is looking at significant cost-cutting, with UNAIDS looking to shed more than half its staff, along with reports of possibly folding it into WHO.

May 2025

Global Health Watch: Further Funding Cuts and “America First” Policies for Research Expand Threats to Global Health

The threats and actions to decimate US biomedical research and global health continued this week as the world marked 100 days of the new administration. A proposed $9.3 billion rescission package would codify unprecedented cuts to NIH, USAID, and global health programs. At the same time, a draft NIH policy may halt funding for research outside the US threatening thousands of global collaborations.

May 2025

Research Matters – Resources to Protect Research Funding 

For more than 30 years, AVAC and partners have worked to protect the infrastructure and funding that drives lifesaving HIV and biomedical research. Today, that mission is more urgent than ever. Funding from the National Institutes of Health (NIH) fuels innovation, drives the economy, and saves lives. Cuts to this support will make America—and the world—poorer, sicker, and less prepared for future health threats.

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April 2025

Global Health Watch: PEPFAR Downgraded, PrEP Access Threatened, and State Dept Reorganized

This week saw a significant reorganization of the State Department and a delay in the foreign assistance “review process”. There were also new threats to PrEP programs, critical HIV services and health systems, and research in South Africa. Read on for key developments, implications, and resources for action.

April 2025

Global Health Watch: Leadership in Flux, Further Cuts to Foreign Aid, a Pandemic Accord

Just three months since the US presidential inauguration, and still more developments affecting the future of HIV prevention, global health leadership, and pandemic preparedness. From African women leaders demanding action to save HIV prevention, to escalating US foreign aid cuts and the fragile progress of WHO’s Pandemic Agreement, this issue break down what advocates need to know now.

April 2025

Despite USG Global Health Collapse, Here Are Several Data Trackers To Support Your Advocacy

With the collapse in support from the US Presidential administration in global health, data sources tracking the HIV response have been lost, from HIV incidence and prevalence to PrEP uptake and disparities among key populations and regions of the world.

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April 2025

showing 1-10 of 1093

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P-Values Blog

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

Advocates Network

AVAC’s email list for organization and individuals interested in timely updates and critical perspectives on developments in biomedical HIV prevention.

Weekly News Digest

A comprehensive round-up of HIV prevention media coverage and scientific publications.

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Each month this podcast uses interviews, discussion and first-person reflections to explore vital topics confronting the field of HIV prevention research.

PxWire

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Pandemic Watch

Pandemic Watch is a curated news digest on the latest pandemic prevention, preparedness, and response (PPPR) news and resources.

Press Releases

A collection of official statements from AVAC.

AVAC in the News

Media clippings featuring AVAC, its staff and close partners in the news media.