Accelerating Product Innovation and Availability

Improving how prevention is delivered

Developing a rich pipeline of options for HIV prevention is essential and must be guided by community priorities that define what products are needed and supported through R&D.

Once approved, interventions typically become widely available in wealthy countries within a few years time. But scaling up new options in lower and middle-income countries lags for years, even decades, with devastating effects on global health, individual lives, and the global effort to end the epidemic.

AVAC’s work supports:

  • Development of timely, effective and affordable prevention options
  • Including community needs and perspectives in R&D
  • Compiling and analyzing market data
  • Producing data, lessons learned, tools, and resources that support product introduction
  • Collaborating with partners to get products faster to market and to scale
  • Sharing and translating information, including around choice in the development and rollout of new products
  • Advocating for the integration of HIV services with sexual and reproductive health

AVAC partners closely with Access Bridge to inform and accelerate product introduction and access. Access Bridge is an independent, Kenya-based not-for-profit rooted in African leadership and global collaboration that was incubated at AVAC. Access Bridge advances timely, sustainable, and equitable introduction of and access to HIV prevention, SRH and related health products.

The Latest on Accelerating Product Innovation

Infographic

Potential Lenacapavir Supply, 2026-28

Lenacapavir has the potential to reach millions — and the momentum is building. Using the current oral PrEP market as a baseline, this graphic estimates what demand for LEN could look like through 2028 and shows how current donor commitments stack up against that opportunity.

Infographic

An Overview of Lenacapavir for PrEP Trials

The PURPOSE trials evaluate the safety and efficacy of injectable lenacapavir (LEN), an investigational antiretroviral (ARV) drug being studied as a potential PrEP product. This graphic shows the latest status of all five trials including the groundbreaking results of PURPOSE 1 and PURPOSE 2.

Report

AVAC Year in Review 2025

This report highlights AVAC’s role as a trusted voice, a translator of science and catalyst for action and advocacy. It reflects an organization ready for the future: supporting African leadership, strengthening bridges from R&D to delivery and preparing for a new chapter as we move forward into our fourth decade as an organization.