Accelerating Product Innovation and Availability

Improving how prevention is delivered

Developing a rich pipeline of options for HIV prevention is essential and must be guided by community priorities that define what products are needed and supported through R&D.

Once approved, interventions typically become widely available in wealthy countries within a few years time. But scaling up new options in lower and middle-income countries lags for years, even decades, with devastating effects on global health, individual lives, and the global effort to end the epidemic.

AVAC’s work supports:

  • Development of timely, effective and affordable prevention options
  • Including community needs and perspectives in R&D
  • Compiling and analyzing market data
  • Producing data, lessons learned, tools, and resources that support product introduction
  • Collaborating with partners to get products faster to market and to scale
  • Sharing and translating information, including around choice in the development and rollout of new products
  • Advocating for the integration of HIV services with sexual and reproductive health

AVAC partners closely with Access Bridge to inform and accelerate product introduction and access. Access Bridge is an independent, Kenya-based not-for-profit rooted in African leadership and global collaboration that was incubated at AVAC. Access Bridge advances timely, sustainable, and equitable introduction of and access to HIV prevention, SRH and related health products.

The Latest on Accelerating Product Innovation

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ARV-Based and Multipurpose Prevention Technology R&D Pipeline

The pipeline of non-vaccine HIV prevention products includes oral pills, vaginal rings, vaginal and rectal gels, vaginal films, long-acting injectable antiretrovirals and more. Also pictured are the range of MPTs in development that aim to reduce the risk of HIV and STIs and/or provide effective contraception for women.

Infographic

The HIV Prevention Pipeline

This graphic shows currently available options for HIV prevention, newly approved and recommended treatment, and those in development.

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Potential Lenacapavir Supply, 2026-28

Lenacapavir has the potential to reach millions — and the momentum is building. Using the current oral PrEP market as a baseline, this graphic estimates what demand for LEN could look like through 2028 and shows how current donor commitments stack up against that opportunity.