P-Values

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

At P-Values, you’ll find updates, perspective, insights and information from staff and partners working on the frontlines of research, advocacy and implementation. P-value is a statistical term for the probability that a trial result is reliable and not the outcome of chance. 

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Global Health Watch: Political Interference in Science, Bethesda Declaration 2.0, UN HLM on HIV Negotiations, ADA Mtg Controversy

From the updated Bethesda Declaration and controversy at the American Diabetes Association annual meeting, to high-stakes negotiations on the UN Political Declaration on HIV/AIDS ahead of the upcoming High-Level Meeting, the politicization of science and public health are on full display this week.

June 2026


HIV Cure Research

As scientific progress accelerates, AVAC’s cure programs are ensuring communities remain at the center of the agenda. Through initiatives like the US HIV Cure Academy, global advocacy convenings and community-led storytelling, AVAC is equipping advocates with the knowledge and networks needed to shape the future of HIV cure research and bridge the gap between complex science and the communities most impacted by HIV.

June 2026


The 2026 US HIV Cure Academy

In April 2026, AVAC, the Well Project and the Martin Delaney Collaboratories brought together skilled advocates together, along with leading researchers and cure experts, for the US HIV Cure Academy. The Academy is designed to strengthen understanding of HIV cure science and build research translation skills in support of advocacy efforts. Learn more.

Prevention Option:

June 2026


Global Health Watch: Research in Peril, Ebola Vaccine Devs, Congress Questions Sec. Of State, Exec Order Makes Firing HHS Employees Easier

A new proposed White House OMB rule seeking greater political oversight of federal grantmaking puts research in peril; vaccine developments accelerate as the Ebola Bundibugyo outbreak grows; the US Secretary of State takes questions from multiple Congressional committees about the future of PEPFAR; responding to the Ebola outbreak; support of Gavi, the Vaccine Alliance; and US global health security.

June 2026


HIV Prevention Advocates Applaud South Africa’s Introduction of Lenacapavir for PrEP

In a landmark moment, South Africa today became the 9th African country to introduce lencapavir (LEN) for HIV prevention. South Africa’s introduction of LEN is especially significant given the country’s central role in shaping the regional HIV response and the global PrEP market. As the largest PrEP market in the world, South Africa’s leadership can help drive the demand, volume, market confidence and lower prices needed to accelerate equitable access across the continent and the world.

Prevention Option:

June 2026


ACTION ALERT: Research in Peril

In an ongoing attempt to decimate and politicize science, the White House Office of Management and Budget proposed sweeping new regulations to significantly expand political interference in federal research funding decisions across all federal grants, threatening science, global health and the HIV/AIDS response.

June 2026


Lenacapavir Arrives in South Africa on Friday

Injectable lenacapavir for PrEP (LEN) is rolling out across Africa faster than any HIV prevention option to date. This Friday, South Africa will become the ninth African country to introduce LEN. Read for updated resources to track this progress and ensure the field moves with speed, scale and equity.

June 2026


Global Health Watch: CDC Directors Warn About PEPFAR, Ebola & Aid Cuts, Policy Developments Threaten Open Science

A commentary by eight former US CDC directors urges the US Department of State to reform PEPFAR, not dismantle it; the growing Ebola outbreak and ongoing hantavirus concerns underscore the risks abrupt changes pose to global health security; and a proposed new US federal grant regulation could significantly expand political influence over scientific funding decisions and research priorities.

May 2026


AI & HIV Newsletter

We are excited to release our first AI & HIV Newsletter! This new quarterly resource will provide advocates and the global community with the information and resources to engage with AI in ways that strengthen equity, protect individuals and communities and prioritize their inclusion, and ensure that technological innovation advances the HIV response rather than undermines it.

May 2026


INTEREST 2026

INTEREST 2026 took place from 12–15 May 2026, in Dar es Salaam, Tanzania. Read reflections and key takeaways from AVAC’s Grace Kumwenda and Access Bridge’s Wawira Nyagah.

May 2026


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P-Values Blog

Discover perspectives on the latest findings, biggest challenges and most exciting successes in our collective work.

Advocates Network

AVAC’s email list for organization and individuals interested in timely updates and critical perspectives on developments in biomedical HIV prevention.

Weekly News Digest

A comprehensive round-up of HIV prevention media coverage and scientific publications.

PxPulse

Each month this podcast uses interviews, discussion and first-person reflections to explore vital topics confronting the field of HIV prevention research.

PxWire

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Pandemic Watch

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Press Releases

A collection of official statements from AVAC.

AVAC in the News

Media clippings featuring AVAC, its staff and close partners in the news media.