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Advocacy: Now more than ever – and AVAC needs you more than ever, too

Join Us at ICASA and the 8th Biomedical HIV Prevention Forum

As seismic shifts in global health funding and strategy unfold, the ICASA conference comes at a pivotal time. For more than three decades, ICASA has served as a critical platform founded by African scientists, activists, and advocates to fight stigma, drive research, and elevate African leadership in the HIV response. This year, this mission is more urgent than ever.

AVAC Statement on the 8th Replenishment of the Global Fund to Fight AIDS, Tuberculosis and Malaria

Global Health Watch Timeline

This timeline tracks selected milestone events in 2025, both massive disruptions in global health along with advocacy responses and wins in the midst of madness.

HIV Prevention R&D at Risk

AVAC’s analysis of the impact of US Government funding cuts, terminated projects, and other policy changes on the HIV prevention research and development (R&D) pipeline, and on HIV research broadly.

The Quest For An HIV Cure — Will It Be Discovered in Africa?

Global Health Watch: Global Fund replenishment, LEN for PrEP arrives, HIV funding uncertain post gov’t shutdown

This week’s newsletter publishes just as the Global Fund’s 8th Replenishment Summit in South Africa is taking place. The Global Fund represents one of the strongest symbols of global solidarity in the fight against HIV, TB, and malaria, but, despite early pledges from several European Union member states and private partners, key donors (including the UK, Germany and France) appear to be stepping back, with smaller or uncertain pledges at this critical moment, and it is not yet clear what the US will do.

Lenacapavir Regulatory Approval

Regulatory approvals, pending decisions, and appeals as of November 2025.

Community Engagement in USG Global Health MoUs

Global Health Watch: Pandemic Accord, US MoU pressure, LEN progress & UK Global Fund cuts

African countries reaffirm support for a new multilateral Pandemic Accord even as pressure mounts to sign bilateral US health agreements. The UK has reduced its upcoming Global Fund pledge just weeks before the replenishment summit. Meanwhile, additional regulatory submissions of LEN for PrEP are being made reflecting accelerated actions and real lessons learned from earlier PrEP rollout.