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My CROI 2026 Notebook: Science, Surprises, and the Big Question of Choice 

VAC Regional Program Manager for Research Engagement Grace Kumwenda shares her CROI 2026 notebook—covering the rapidly expanding menu of long-acting prevention options, innovative delivery models bringing PrEP closer to communities, and the big question running through it all: how much choice is enough, and are our systems ready to deliver it?

CROI 2026: Hot Takes

Returning to the CROI conference after several years, AVAC Senior Program Manager Cindra Feuer gives her reflections on a field that’s leaner, fiercer, and fighting back—from promising long-acting ARV pipelines to a striking 70% HIV incidence decline in the SEARCH trial and a spirited PEP Think Tank on what comes next.

Source of Lenacapavir for PrEP Supply to Early Adopter Countries

The Global Fund, with support from CIFF, and PEPFAR have jointly committed to reaching up to two million people with injectable lenacapavir for PrEP over three years. Supply of LEN began arriving in countries in late 2025 with service delivery planned to start in early 2026.

Forward in SYNChronicity through Research and Care

The Power of Advocacy: Keeping state, national and global progress connected

What Happens When the Next Pandemic Hits?

Global Health Watch: US Appropriated Science Funds Remain Frozen, Lenacapavir Rollout Advances + South Africa Pursues Local Production

In this issue, we look at delays in the release of US science funding, despite congressional approval, and new developments from South Africa and AVAC shaping the global rollout of HIV prevention options. 

STIWatch Quarterly Newsletter

As many global health fields reassess their reliance on US government funding for research and development, the STI field—already underfunded and reliant on alternate donors—now faces even greater uncertainty. In this newsletter, we share a new STI resource for advocates and highlight the top issues we’re monitoring as events continue to unfold.

Introducing Access Bridge, Our Partner in Product Introduction

AVAC is excited to introduce Access Bridge. Incubated over the past decade at AVAC as part of our Product Introduction and Access team, Access Bridge is an independent, Kenya-based nonprofit organization advancing timely, sustainable and equitable introduction of and access to HIV prevention, sexual reproductive health and related health products.

Global Health Watch: Zimbabwe steps away from US health MoU, new domestic funding in SA, LEN launched in Kenya + Zim, investment case for Global Fund

This week’s issue covers Zimbabwe’s decision to halt negotiations on its Memorandum of Understanding with the US for global health funding; new domestic funding in South Africa; a new investment case for US funding for the Global Fund; the launch of LEN in Kenya and Zimbabwe; and key takeaways from CROI 2026.