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Global Health Watch: Health Policy Decisions Reversed, FY26 US Global Health Funding, America First MoUs Scrutinized & LEN for PrEP Advances

The US foreign assistance budget, if enacted, would restore some global health funds in a broader context of uncertainty, as US bilateral “America First” health MoUs advance without transparent plans for implementation or accountability. At the same time, abrupt reversals by the US Department of Health and Human Services of troubling health policy decisions underscore the Administration’s instability. Meanwhile, momentum around lenacapavir continues, recently approved by Brazil and with additional funding from Unitaid to reach more populations in South Africa and Zambia.

January 2026


Lenacapavir Implementation Studies

Ongoing and planned implementation studies for the lenacapavir as of January 2026.

Prevention Option:

January 2026


January 2026


HIV Prevention Product Overview

The graphic provides an overview of PrEP products currently available and in late-stage clinical trials. 

January 2026


Lenacapavir Regulatory Approval

Regulatory approvals, pending decisions, and appeals as of January 2026.

Prevention Option:

January 2026


The Future of HIV Prevention with Dr. Jeanne Marrazzo

On January 20, join us and Jeanne Marrazzo, IDSA CEO and AVAC board member, for The Future of HIV Prevention: A People’s Research Agenda for Speed, Scale and Equity, a webinar exploring the PRA’s people-centered framework, what the PRA tracks, why it matters and what’s at stake.

January 2026


People’s Research Agenda 2025 Update Summary Table

The People’s Research Agenda sets out a people-centered framework for equitable and accelerated R&D and product introduction. It tracks the science, shows where investments align—or fail to align—with community-defined priorities, and spotlights critical gaps in the pipeline of prevention options needed to meet the diverse realities of all populations.

January 2026


Cabotegravir Regulatory Approval

Regulatory approvals and those pending for cabotegravir as of January 2026.

Prevention Option:

January 2026


HIV Vaccine Clinical Trials Pipeline

This graphic summarizes the state of HIV vaccine research, detailing the different immunological approaches in clinical trials, the specific candidates being studied, and the collaborative networks of funders and developers working toward an effective vaccine.

January 2026


Global Health Watch: Assault on US vaccine policy, contradictions in HPV and HIV vaccine science; 14 countries sign America First MOUs

The assault on vaccine policy and confidence intensified this week as the US overhauled its childhood immunization schedule. Beyond the US, 14 countries have now signed bilateral health agreements with the US under the America First Global Health Strategy. At the same time, the US President signed a new executive order withdrawing the US from and defunding over 60 international organizations and treaties. And Germany reportedly plans to cut its funding by half for the World Health Organization’s Hub for Pandemic and Epidemic Intelligence.

January 2026


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