Search

In the Midst of Chaos, a Historic Opportunity this World AIDS Day

World AIDS Day in 2025 comes at a moment of unprecedented change. Over 60 years of investment in global health, forty years of innovation and progress in the fight to end the HIV epidemic, and many of the critical programs that provide access to HIV prevention in high burden countries are in disarray and at risk of collapse. Yet, in the midst of the chaos, there’s a historic opportunity to defeat HIV by scaling-up the breakthrough technology of long-acting injectable PrEP.

Global Health Watch: PEPFAR negotiations leave communities behind, Global Fund replenishment falls short, continued chaos at CDC and NIH

Decisions and actions this week further weaken the global HIV response — from the exclusion of communities in the new PEPFAR US global health strategy negotiations to a Global Fund replenishment that falls short. Major disruptions at the US CDC and NIH and the White House “skipping” World AIDS Day — continue the erosion of accountability, trust, and the integrity of the public health system.

The Science of HIV Cure: What communities need to know

24 Hour Marathon to Save AIDS Research

AVAC worked together with a volunteer coalition of the nation’s leading HIV researchers and advocates to conceptualize, organize, and host the 24-Hour Marathon to Save HIV Research, which featured interactive presentations, discussions, and learning sessions to raise awareness about the lifesaving contributions of HIV research.

Source of Programmatic Cabotegravir for PrEP Supply

The first supplies of CAB for programmatic use (as opposed to use in implementation studies) began to arrive in countries in 2024. Currently, 16 countries are rolling out CAB for programmatic use, with the majority of supply provided by PEPFAR, and some additional quantities procured by the Global Fund.

Lenacapavir Regulatory Approval

Regulatory approvals, pending decisions, and appeals as of November 2025.

Advocacy: Now more than ever – and AVAC needs you more than ever, too

2025 has been a year like no other. During these challenging times, AVAC’s Global Health Watch has been the go-to source for tracking and analyzing attacks on global health and the HIV response, pandemic preparedness, and human rights: from the US government’s foreign aid freeze and subsequent funding collapses to the politicization of science and erosion of public health infrastructure.

Join Us at ICASA and the 8th Biomedical HIV Prevention Forum

As seismic shifts in global health funding and strategy unfold, the ICASA conference comes at a pivotal time. For more than three decades, ICASA has served as a critical platform founded by African scientists, activists, and advocates to fight stigma, drive research, and elevate African leadership in the HIV response. This year, this mission is more urgent than ever.

AVAC Statement on the 8th Replenishment of the Global Fund to Fight AIDS, Tuberculosis and Malaria

Global Health Watch Timeline

This timeline tracks selected milestone events in 2025, both massive disruptions in global health along with advocacy responses and wins in the midst of madness.