Language for HIV Cure

This document shares up-to-date, community-preferred terminology within cure research.

Avac Event

ICASA 2023

Join AVAC and partners for the biennial International Conference on AIDS and Sexually Transmitted Infections (ICASA), in Harare, Zimbabwe December 4-9. More than 30 of our partners will convene at the meeting to champion community leadership and amplify their role in shaping local, national and global responses and delivering impactful advocacy. Community leadership on a range of issues are instrumental to: 

  • Accelerate and expand access to proven prevention options that people want and need. 
  • Dismantle the structural barriers to health faced by key populations. 
  • Intensify demands for robust domestic and global funding for health. 
  • Integrate HIV services with sexual and reproductive health. 
  • And much more. 

Scroll down for a roadmap to ICASA’s prevention program, and details on sessions and events that you won’t want to miss. 

Sessions of Interest

Sunday, December 3

  • Biomedical Prevention Forum 
    9:00-15:00 GMT 
    The Biomedical Prevention Forum will be held as a hybrid event bringing together advocates, civil society representatives, researchers, government officials and front-line providers to explore and discuss the latest advancements, challenges, and opportunities in biomedical HIV prevention, while emphasizing the importance of choice and its transformative impact on HIV prevention efforts. This is an open event. Register here. 
  • Key Populations Preconference 
    9:00-15:00 GMT 
    The Africa Key Populations Experts Group (AKPEG), African Sex Workers Alliance (ASWA), the African Network of People Using Drugs (AfricanPUD) and African Queer Youth Initiative (AQYI) Advocates for Prevention of HIV and AIDS in Africa (APHA), Global Black Gay Men Connect (GBGMC) and partners will host a safe platform to deliberate on the state of the HIV epidemic among Key Populations and to determine the stumbling blocks for progress on the path that ends AIDS for Key Populations.

Monday, December 4

Tuesday, December 5

  • Advancing Integrated Biomedical Prevention: Best Practices from Zimbabwe (Session 2) 
    8:45-09:30 GMT
    This satellite session will discuss best practices and lessons learned from the delivery of biomedical HIV prevention and Voluntary Medical Male Circumcision services as we work to further universal health coverage and robust health systems. Partners will launch a global call to action to unite, mobilize, and advocate for continued prioritized funding, sustained commitment, and strategic integration of VMMC into national and global prevention strategies.
  • Catalyzing a sustainable HIV prevention agenda: Approaches to expand local action on global commitments
    10:45-11:30 GMT
    Leveraging new strategic plans for HIV prevention, including the PEPFAR’s 5-year Strategy and UNAIDS’ Prevention Road Map, this satellite session will discuss combination prevention in the context of a sustainable HIV response and highlight a variety of approaches and models that leverage country and stakeholder-led innovations to meet the challenge.
  • Coordinating Implementation Science for CAB for PrEP: BioPIC’s Implementation Study Tracker 
    12:25-12:35 GMT
    In this oral abstract session, AVAC will present a new dashboard, which reflects all currently known activities relating to implementation research, modelling, clinical research, and landscaping for new late-stage biomedical HIV PrEP options, including cabotegravir for PrEP and the dapivirine vaginal ring.
  • Policy, Politics and HIV Management 
    13:05-13:50 GMT
    In this oral abstract session, Princess Mharire from Pangaea Zimbabwe AIDS Trust (PZAT) will present, Beyond Metrics: How the Simple Participatory Assessment of Real Change (SPARC) Tool Provides a Holistic Approach to Advocacy Measurement, and Joseph Njowa of PZAT will share the COMPASS MERL model in a presentation, Innovative tools for planning, monitoring, and evaluation of advocacy campaigns. 

Wednesday, December 7

Friday, December 8

  • Strengthen integration for better SRHR outcomes 
    10:45-11:30 GMT
    This concurrent session will feature Advocates for Prevention of HIV and AIDS in Africa’s (APHA) Yvette Raphael and will explore linkages between unintended pregnancies, unsafe abortion, and HIV.
  • HIV Prevention-Right Place, Right time 
    13:05-13:50 GMT
    This concurrent session will feature Maureen Luba of AVAC, Definate Nhamo of PZAT and Yvette Raphael of APHA. 

AVAC and Partner Poster Presentations

Tuesday, December 5 

  • Maximizing private pharmacies for PrEP delivery to increase uptake: Lessons learnt from the Community Retail Pharmacy Distribution Point, Ruth Akulu 

Wednesday, December 6 

  • Journalist Training: A Key Advocacy Strategy, Catherine Madebe
  • Perceptions on the new biomedical HIV prevention methods among adolescent girls and young women in tertiary institutions in Zimbabwe, Cleo Makura
  • Lessons from Crisis Response from TaNPUD in Enhancing Harm Reduction from 2015 to 2018, Marineus Mutongore
  • Implementing Community led Monitoring for improved quality of HIV services in Tanzania, Mathew Kawogo
  • Impact of social media exposure on HIV services uptake among Tanzanian Young people: Implications for enhancing the HIV response, Marineus Mutongore
  • Effective Strategies for Operating COWLHA support groups of Adolescents Living with HIV: Case of Mangochi and Chikwawa Districts of Malawi, Harry Madukani

Thursday, December 7 

  • Understanding Choice of HIV Prevention Options among Adolescent Girls and Young Women (AGYW) in Zambia, Natasha Mwila
  • Leveraging HIV to Build a Global Health Research and Development (R&D) Equity Advocacy Agenda, John Meade
  • Championing advocacy for domestic resource mobilization for health research and development in Africa, Ethel Makila

Friday, December 8 

  • Rural Youth: Underserved and Unsafe When Seeking Care, Liyema Somnono
  • Redefining Coalition Governance and Leadership in Support of Decolonizing Global Health: The Evolution of the COMPASS Coalition, Roberta Sutton
  • Collaborative Monitoring & Evaluation to Support Learning and Strengthen Advocacy Coalitions: The MERL Hub, Grace Tetteh
  • Realities faced by street children predisposing them to HIV and STIs in Dodoma and Dar es Salaam Cities in Tanzania, Simon Shilagwa 

A Comprehensive Approach for Progress

Ending the Epidemic

ClusterF*#k: Molecular HIV Surveillance, Criminalization, and The Real Risks to PLHIV

Tuesday, July 18 at 11:00 AM–12:30PM ET

Advocates Brian Minalga (Deputy Director of the Office of HIV/AIDS Network Coordination), Amir Sadeghi (Policy and Advocacy Manager at the The Center for HIV Law and Policy), and Andy Spieldenner (Executive Director of MPact Global Action) will explore the intersection of surveillance, bodily autonomy and criminalization.

This webinar is co-sponsored by The Center for HIV Law and Policy, MPact Global Action, and the Office of HIV/AIDS Network Coordination.

Recording / Slides / Resources

The Latest Resources From AVAC

AVAC has new resources and information covering mpox, UN negotiations on a declaration on pandemic preparedness, and highlights from the annual South African AIDS Conference (SAAIDS). In addition, be sure to scroll down for upcoming webinars on HIV and STI conferences and more!

Advocacy in Action: An update on the moving pieces of PPPR
Pandemic prevention, preparedness and response (PPPR) involves numerous initiatives to ensure the world is ready to respond to existing and future pandemics. UN members are in the midst of negotiating the language of a declaration on PPPR, which will commit heads of state and their governments to agreements on global coordination. And similar negotiations are underway on a global Pandemic Accord.

Check out, Our Take: Is the UN Declaration on PPPR and the Pandemic Accord going in the right direction? This blog by AVAC’s Sam Rick explores an analysis, conducted by AVAC and partners, of the current drafts of the Pandemic Accord and the UN Declaration on PPPR—and their implications for equity in global health. For background, see AVAC’s Advocates Guide for PPPR in 2023 and the recording from a recent webinar, The Road to and Beyond High-Level Meeting on UHC and PPR.

SA AIDS
The 11th annual South Africa AIDS Conference took place in June 20-23 in Durban, South Africa. AVAC and CASPR partners hosted a buzzing Research Literacy Networking Zone with a rich schedule of programs—see the full schedule here, and recordings here. We’re also super excited to report the launch of the Young Women’s HIV Prevention Council at SAAIDS—stay tuned for more about this dynamic group of women soon!

Updated PrEP Product Introduction Country Planning Matrix
Check out our updated Product Introduction Country Planning Matrix that tracks the regulatory status of cabotegravir for PrEP and the dapivirine vaginal ring, along with related implementation research, procurement plans, and oral PrEP provision.

ICYMI: Recordings of recent webinars

  • Mpox: Research, prevention and overcoming disparities—PrEP In Black America, PrEP4All, Treatment Action Group and AVAC co-hosted a webinar with an expert panel who explored the latest research, precautions individuals can take to protect themselves, effectiveness of vaccines, and the ongoing fight to address disparities in infection rates and uptake of vaccines, treatments and tests that impact Black communities. It is important for advocates to remain engaged, and for affected communities to be supported in completing their two-dose mpox vaccine regimens. Listen to the webinar and check out the resources.
  • PrEP That Booty: The latest on rectal microbicide research for the back door—The latest webinar from The Choice Agenda explored new research on rectal microbicides and advocacy for non-systemic options. Find slides and related resources here and watch for the recording coming soon.

Upcoming Webinars!
July 18: ClusterF*#k: Molecular HIV Surveillance, Criminalization, and The Real Risks to PLHIV
Register here
August 3: Tales from Two Cities: HIV and STI research highlights from IAS in Brisbane and ISSTDR in Chicago
Register here

Cumulative Number of PrEP Initiations for Q1 of 2023

PrEP That Booty: The latest on rectal microbicide research for the back door

Thursday, June 29 at 9:00 AM–10:30AM ET

Most of what we hear about regarding the HIV prevention pipeline is about long-acting, longer-acting, and even longer-acting products that deliver drug throughout the body and require a trained clinician to deliver. However, these attributes are not desirable to many folks, and communities want a range of choices. Researchers and advocates for years have been working on HIV prevention products specifically for the back door (rectum) to provide protection during anal intercourse. These products are user-controlled, non-systemic (the drug stays in the booty and only the booty), and are short-acting, so you don’t have to commit to having a prevention drug in your body for a year or longer. Join us for a dynamic discussion regarding the latest research on Booty PrEP – aka rectal microbicides – with our multi-talented panel.

Speakers include: Jonathan Baker, PA, Laser Surgery Care, Dr. Craig Hendrix, Johns Hopkins, Juan Michael Porter II, The Body, and Dr. Sharon Riddler, University of Pittsburgh

Recording / Slides / Resources

Avac Event

SA AIDS 2023

June 20, 2023

Taking place in Durban from June 20-23, the theme of the 11th South Africa AIDS Conference (SA AIDS) is “act, connect and end the epidemic”.

Registration and Draft Program
Register for the conference and view the draft program.

Research Literacy Networking Zone
At the conference, AVAC and a number of partners will be hosting the Research Literacy @ Networking Zone. More information available here.

Follow Along From Near and Far
Watch this space and/or sign up for our Advocates’ Network mailing list to stay-up-date on the latest at SA AIDS 2023. AVAC will also be posting from the conference on Twitter. Click here for the official SA AIDS Twitter account.

A Recap of Resources: UNAIDS meeting, HVAD webinars and more

In this round up of updates and resources, you’ll find a read-out of the May UNAIDS high-level meeting in Geneva, two webinars that spotlight critical issues for vaccines R&D and the potential of broadly neutralizing antibodies, and an upcoming webinar looking at alternatives to long-acting PrEP. Read on and join us!

The HIV Response at UNAIDS High-level Meeting
A high-level meeting in Geneva, held by UNAIDS last month on the margins of the World Health Assembly, brought together advocates and experts through the Global HIV Prevention Coalition to discuss where action is needed most to bolster HIV response and advance global health equity. Read AVAC’s summary of the meeting in our latest P-Values blog.

title card with presentation info

Vaccines in 2023 and Beyond
AVAC hosted two webinars in commemoration of HIV Vaccine Awareness Day. They offer a snapshot on the state of the field for an HIV vaccine, and explore considerations for the development and delivery of vaccines against future pandemics. Check them out below and read more in our HVAD one-pager!

What’s All the Buzz About: mRNA, manufacturing, vaccines access Local production has emerged as an essential part of the solution for ensuring sustainable and equitable supplies of vaccines in low- and middle-income countries. This webinar explored how local manufacturing and the new mRNA Hub in South Africa could facilitate access and support R&D. Check out the summary and recording.

To bNAb or not to bNAb? The case for broadly neutralizing antibodies AVAC and partners explored the potential role of bNAbs in prevention, the status of research and development, and implications for HIV vaccine research. Check out the summary and recording.

Upcoming
PrEP In Black America Presents Mpox Webinar
PrEP in Black America alongside a panel of experts will discuss the impact of mpox on Black communities, advocacy and mobilization to keep our communities safe, and information on vaccine effectiveness. Tuesday, June 20 at 2:00 PM to 3:30 PM ET. Register here.

PrEP That Booty: The latest on rectal microbicide research for the back door
Most of the coverage of the HIV prevention pipeline is about long-acting, longer-acting, and even longer-acting products that deliver drug throughout the body and require a trained clinician to deliver. However, these attributes are not desirable to many folks, and communities want a range of choices. Learn more about the alternatives at this webinar. Thursday, June 29 at 9:00 AM to 10:30 AM ET. Register here.

HIV Vaccine Awareness Day (HVAD) 2023

May 18th is recognized as HIV Vaccine Awareness Day (HVAD), and this year it is a time of deep reflection and potential. Three major HIV vaccine trials have ended in no efficacy since 2020, but the field knows more than ever that a vaccine is still needed for a durable and sustainable end to the pandemic – and has new insights into possible vaccine strategies that might one day effectively protect against HIV.

This year, AVAC and CASPR partners are casting a spotlight on the many issues and opportunities for HIV vaccine science. See below for three important conversations

Podcast: Listen to AVAC’s PxPulse podcast, Evolving Strategies for an HIV Vaccine: One researcher explains where the field is going and why, featuring Katy Stephenson of Harvard Medical School, Beth Israel Deaconess Medical Center, and the Center for Virology and Vaccine Research. In conversation with AVAC’s Jeanne Baron, Katy provides an accessible breakdown on the status of the field of HIV vaccine research, including details on recent trial results that proved ineffective and what’s next (and exciting) in HIV vaccine advocacy and research.

“The field needs to expand the diversity of scientists who are thinking of new ideas. We haven’t gotten far with the ideas coming out exclusively from the United States and Europe. We need to bring in young scientists of diverse backgrounds all over the world to think of ideas we can’t even imagine.”

“We now know that non-broadly neutralizing antibodies don’t work, but broadly neutralizing antibodies can work. It’s a big milestone in the field to have that kind of knowledge now.”

Katy Stephenson, Harvard Medical School and Beth Israel Deaconess Medical Center, and the Center for Virology and Vaccine Research

Webinars: AVAC brought together partners, advocates and other experts for two vaccine webinars. The first, on local manufacturing production, takes on this essential part of the solution for ensuring sustainable and equitable supplies of vaccines in low- and middle-income countries. The second explores the development of broadly neutralizing antibodies (bNABs) and their potential in HIV prevention. Check out the recording and slides for both.

What’s All the Buzz About: mRNA, manufacturing, vaccines access – featuring Caryn Fenner of Afrigen Biologics, Ike James of Medicines Patent Pool, and Mike Frick of Treatment Action Group. 

“LMICs (Low- or Middle-Income Country) are not only the consumers of IP (Intellectual Property), we are the generators of IP!” Caryn Fenner, Afrigen Biologics

“It’s important for us in the Global North to know that vaccine technology didn’t start in Global North and was often taken from others.” Mike Frick, Treatment Action Group.

“Engagement and commitment [is needed], not only when a pandemic exists, but long-term commitments are key to follow through on.” Ike James, Medicine Patents Pool

To bNAb or not to bNAb? The case for broadly neutralizing antibodies – featuring Slim Abdool Karim of CAPRISA, Pervin Anklesaria of Bill & Melinda Gates Foundation, Khadija Richards of Wits RHI, and Huub Gelderblom of HIV Vaccine Trials Network (HVTN).

“The scientific complexities of bNAbs require a more attuned focus on community engagement… And it will require a high degree of validating [people’s] lived experience.”, Khadija Richards, Wits RHI.

“The hope is that if bNAbs are effective in prevention, they create a pathway towards a vaccine.” Slim Abdool Karim, CAPRISA

“To close the gap between scientific innovation and globally accessible and affordable bNAb combination products…we certainly need innovation in manufacturing. It is a long-term process and it’s not going to happen overnight. But we do need to start now.” Pervin Anklesaria, Bill & Melinda Gates Foundation

“What I see is actually multiple modes of PrEP available, and then people can make choices depending on what works for them.” Huub Gelderblom of the HIV Vaccine Trials Network on the potential of bNAbs as PrEP